nodal signaling pathway

Known as: nodal signaling, nodal signalling pathway 
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Activin/Nodal signaling is required for maintaining pluripotency and self-renewal of mouse epiblast stem cells and human… (More)
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Highly Cited
2010
Highly Cited
2010
Both intercellular signaling and epigenetic mechanisms regulate embryonic development, but it is unclear how they are integrated… (More)
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Highly Cited
2009
Highly Cited
2009
Human pluripotent stem cells from embryonic origins and those generated from reprogrammed somatic cells share many… (More)
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Highly Cited
2005
Highly Cited
2005
Human embryonic stem cells (hESCs) self-renew indefinitely and give rise to derivatives of all three primary germ layers, yet… (More)
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Highly Cited
2005
Highly Cited
2005
The asymmetric positioning of internal organs on the left or right side of the body is highly conserved in vertebrates and relies… (More)
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Highly Cited
2002
Highly Cited
2002
The EGF-CFC gene Cripto encodes an extracellular protein that has been implicated in the signaling pathway for the transforming… (More)
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Highly Cited
2001
Highly Cited
2001
Pitx2 is left--right (L--R) asymmetrically expressed initially in the lateral plate and later in primordial visceral organs. The… (More)
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2001
2001
Nodal, a member of the transforming growth factor beta (TGF-beta) superfamily, is implicated in many events critical to the early… (More)
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Highly Cited
1999
Highly Cited
1999
Mammalian lefty and zebrafish antivin form a subgroup of the TGF beta superfamily. We report that mouse mutants for lefty2 have… (More)
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Highly Cited
1999
Highly Cited
1999
The embryonic midline is crucial for the development of embryonic pattern including bilateral symmetry and left-right asymmetry… (More)
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