nitrosocimetidine

Known as: Guanidine, N'-cyano-N-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-N-nitroso- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2006
02419802006

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
The nitrosated form of cimetidine (Tagamet), nitrosocimetidine (NC), belongs to a group of nitrosoamidines in which the mutagenic… (More)
Is this relevant?
1986
1986
The acute toxicity of N-nitrosocimetidine, the nitrosated derivative of the histamine H2-receptor blocking agent cimetidine, was… (More)
Is this relevant?
1985
1985
Cimetidine (CM), a drug widely prescribed for ulcers, readily undergoes nitrosation to form nitrosocimetidine (NCM), a genotoxic… (More)
Is this relevant?
1984
1984
N-Nitrosocimetidine, a nitroso derivative of the drug cimetidine, was given to groups of 20 male and 20 female rats in drinking… (More)
  • table 2
Is this relevant?
1983
1983
The widely used drug cimetidine (Tagamet) can be nitrosated in the presence of nitrite and under mild acid conditions to form a… (More)
  • table 2
  • table 3
Is this relevant?
1982
1982
The ability of the nitroso derivative of the drug cimetidine to interact with cellular macromolecules in the intact rat was… (More)
Is this relevant?
1982
1982
N-Methyl-N'-nitro-N-nitrosoguanidine (MNNG) has been reported to induce BHK-21/Cl 13 cell growth in agar suspension. To determine… (More)
Is this relevant?
1981
1981
N-Nitrosocimetidine (NC) induces significant numbers of sister chromatid exchanges (SCE) and chromosome aberrations in cultured… (More)
Is this relevant?
1980
1980
The DNA of a transformed epithelial mouse cell line was studied by means of the alkaline filter elution test. Addition of N… (More)
Is this relevant?
1980
1980
The major product of reaction of cimetidine in 2 M hydrochloric acid in the prescence of excess sodium nitrite is a mono-nitroso… (More)
Is this relevant?