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nitrosocimetidine

Known as: Guanidine, N'-cyano-N-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-N-nitroso- 
National Institutes of Health

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2 relations

Broader (1)

Cimetidine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Species Differences in Blood-mediated Nitrosocimetidine Denitrosation 1
Nitrosocimetidine (NC) is the nitrosated derivative of cimetidine ( 1agamet), a p.o. administered drug used widely in the… 
2006
2006
plus Chronic Lifetime Exposure Nitrosocimetidine on Tumors in Mice following Transplacental Effects of Cimetidine , Nitrite , Cimetidine plus Nitrite , and Updated
Cimetidine (CM), a drug widely prescribed for ulcers, readily undergoes nitrosation to form nitrosocimetidine (NCM), a genotoxic… 
1990
1990
Microsomally-mediated denitrosation of nitrosoguanidinium compounds.
A major metabolic fate of 1-methyl-2-nitro-1-nitrosoguanidine (MNNG) and nitrosocimetidine (NC) in rodents is denitrosation to… 
1989
1989
N-nitrosocimetidine as an initiator of murine skin tumors with associated H-ras oncogene activation.
N-Nitrosocimetidine (NCM) is a derivative of the drug cimetidine, a methylguanidine derivative used in the treatment of peptic… 
1982
1982
No evidence of carcinogenicity of N-nitrosocimetidine in rats.
Cimetidine is a histamine H2-antagonist. Since in vitro formed N-nitrosocimetidine (NC) has been shown to be genotoxic, we… 
Highly Cited
1981
Highly Cited
1981
Methylation of DNA by nitrosocimetidine in vitro.
Several clinical reports have implied that the administration of cimetidine, a widely used and very effective drug for the… 
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