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nitroimidazole catabolic process

Known as: nitroimidazole breakdown, nitroimidazole catabolism, nitroimidazole degradation 
The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring… 
National Institutes of Health

Papers overview

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2007
2007
Synthesis, characterization and preliminary biological evaluation of [Cu-64] ethhylenedicysteine-nitroimidazole and comparative studies with [F-18] fluoromisonidazole
Review
2004
Review
2004
Pharmacokinetics in experimental and clinical chemotherapy
In his recent excellent editorial Moore [1] described the principal difficulty arising from the use by experimental… 
Review
1993
Review
1993
Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference toin vivo methods of evaluation
SummaryThe nitroimidazole, RSU1069, has been shown to have a very high differential toxicity towards hypoxic cells compared to… 
1992
1992
SYNTHESIS OF 2-ACETYL-L-METHYL-5- NITROIMIDAZOLE
1990
1990
Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
The efficacies of a series of potential prodrugs of RSU-1069 and its alkyl-aziridine analogues were assessed. These 1-(2… 
Review
1989
Review
1989
[Amebiasis. Medical treatment. Is there anything better than metronidazole?].
Since 1961, when Cosar pointed out for the first time that metronidazol was a useful pharmacological agent against E. histolytica… 
1985
1985
Pre-clinical toxicity studies on the new nitroimidazole 1-methylsulphonyl-3-(1-methyl-5-nitroimidazole-2-yl)-2- imidazolidinone.
Administration of 1-methylsulphonyl-3-(1-methyl-5-nitro-2-imidazole-yl)-2-imidazolidinone (Go 10213) at a dose of 5000 mg/kg to… 
1984
1984
Association of the radiosensitizers metronidazole and misonidazole (RO-07-0582) with bovine serum albumin. Effect of urea and ionic strength.
The stability of association of nitroimidazole radiosensitizers (metronidazole and misonidazole) with bovine serum albumin (BSA… 
1984
1984
Misonidazole neurotoxicity in rats: Part I
SummaryThe effects of misonidazole (MISO) on brain stem evoked potentials (BAEPs) and cortical evoked potentials (CEPs) were… 
1979
1979
High-performance liquid chromatographic determination of the nitroimidazole azanidazole in human plasma and urine.
Azanidazole can be measured in plasma and urine by reversed-phase high-performance liquid chromatography employing UV detection…