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nitrile hydratase

 
National Institutes of Health

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2 relations

Broader (1)

Hydro-Lyases
nitrile hydratase activity

Papers overview

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2012
2012
Improving stability of nitrile hydratase by bridging the salt-bridges in specific thermal-sensitive regions.
The regions and types suitable mutations for bridging salt-bridges to intensify enzyme stability are identified in this study… Expand
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Highly Cited
2004
Highly Cited
2004
The superiority of the third-generation catalyst, Rhodococcus rhodochrous J1 nitrile hydratase, for industrial production of acrylamide
As the third-generation biocatalyst for industrial production of acrylamide, the superiority of Rhodococcus rhodochrous J1… Expand
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Highly Cited
2003
Highly Cited
2003
Characterisation of nitrilase and nitrile hydratase biocatalytic systems
Biocatalytic transformations converting aromatic and arylaliphatic nitriles into the analogous related amide or acid were… Expand
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2001
2001
Crystal structure of cobalt-containing nitrile hydratase.
The crystal structure of cobalt-containing nitrile hydratase from Pseudonocardia thermophila JCM 3095 at 1.8 A resolution… Expand
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Review
1998
Review
1998
Metalloenzyme nitrile hydratase: Structure, regulation, and application to biotechnology
Nitrile hydratase (NHase), which catalyzes the hydration of nitriles to amides, has been used in the industrial production of… Expand
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Highly Cited
1998
Highly Cited
1998
Novel non-heme iron center of nitrile hydratase with a claw setting of oxygen atoms
The iron-containing nitrile hydratase (NHase) is a photoreactive enzyme that is inactivated in the dark because of persistent… Expand
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Highly Cited
1997
Highly Cited
1997
Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold.
BACKGROUND Nitrile hydratases are unusual metalloenzymes that catalyze the hydration of nitriles to their corresponding amides… Expand
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1997
1997
A stereoselective cobalt-containing nitrile hydratase.
Nitrile hydratase from Pseudomonas putida NRRL-18668 has been purified and characterized. The purified enzyme catalyzes the… Expand
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Highly Cited
1996
Highly Cited
1996
Characterization of the gene cluster of high-molecular-mass nitrile hydratase (H-NHase) induced by its reaction product in Rhodococcus rhodochrous J1.
The 4.6-kb region 5'-upstream from the gene encoding a cobalt-containing and amide-induced high molecular mass-nitrile hydratase… Expand
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1991
1991
Purification, cloning, and primary structure of a new enantiomer-selective amidase from a Rhodococcus strain: structural evidence for a conserved genetic coupling with nitrile hydratase.
A new enantiomer-selective amidase active on several 2-aryl propionamides was identified and purified from a newly isolated… Expand
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