Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

nicotinic receptor alpha4beta2

Known as: receptor, nicotinic alpha4beta2, nAChRalpha4beta2, nicotinic receptors alpha4beta2 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Nicotinic Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pre‐clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence
Background and purpose:  Smoking cessation trials with three high‐affinity partial agonists of α4β2 neuronal nicotinic… Expand
Highly Cited
2009
Highly Cited
2009
Reduced alpha4beta2*-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease.
CONTEXT Cognitive or depressive disorders are frequently noted in patients with Parkinson disease (PD) and may be related to… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Review
2009
Review
2009
nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms.
The identification and characterization of drugs for the treatment of cognitive disorders has been hampered by the absence of… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Review
2009
Review
2009
The road to discovery of neuronal nicotinic cholinergic receptor subtypes.
The discovery that mammalian brain expresses the mRNAs for nine different nicotinic cholinergic receptor subunits (alpha2-alpha7… Expand
Highly Cited
2008
Highly Cited
2008
Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure
Adolescence is a time of significant brain development, and exposure to nicotine during this period is associated with higher… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
2006
2006
Untranslated region-dependent exclusive expression of high-sensitivity subforms of alpha4beta2 and alpha3beta2 nicotinic acetylcholine receptors.
alpha4beta2 nicotinic acetylcholine receptors (nAChRs) are recognized as the principal nicotine binding site in brain… Expand
2004
2004
Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro.
The subtype-specificity of newly synthesised epibatidine-related compounds, norchloro-fluoro-homoepibatidine (NCFHEB) and… Expand
Highly Cited
2000
Highly Cited
2000
Novel potent ligands for the central nicotinic acetylcholine receptor: synthesis, receptor binding, and 3D-QSAR analysis.
In the past few years the focus on central acetylcholine receptors has shifted from compounds with affinity for muscarinic… Expand
1998
1998
Open-channel blockers at the human alpha4beta2 neuronal nicotinic acetylcholine receptor.
To extend our knowledge of the pharmacological profile of human alpha4beta2 neuronal nicotinic receptors, we investigated the… Expand
Highly Cited
1997
Highly Cited
1997
Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca2+ Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors
A mutation (S247F) in the channel-lining domain (M2) of the α4 nicotinic acetylcholine receptor (AChR) subunit has previously… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE