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nicotinic receptor alpha4beta2
Known as:
receptor, nicotinic alpha4beta2
, nAChRalpha4beta2
, nicotinic receptors alpha4beta2
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Nicotinic Receptors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pre‐clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence
H. Rollema
,
A. Shrikhande
,
+12 authors
D. Bertrand
British Journal of Pharmacology
2010
Corpus ID: 8990005
Background and purpose: Smoking cessation trials with three high‐affinity partial agonists of α4β2 neuronal nicotinic…
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Highly Cited
2009
Highly Cited
2009
Reduced alpha4beta2*-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease.
P. Meyer
,
K. Strecker
,
+13 authors
J. Schwarz
Archives of General Psychiatry
2009
Corpus ID: 34392206
CONTEXT Cognitive or depressive disorders are frequently noted in patients with Parkinson disease (PD) and may be related to…
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Review
2009
Review
2009
nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms.
M. Sarter
,
V. Parikh
,
W. Howe
Biochemical Pharmacology
2009
Corpus ID: 6436162
Review
2009
Review
2009
The road to discovery of neuronal nicotinic cholinergic receptor subtypes.
A. Collins
,
O. Salminen
,
M. Marks
,
P. Whiteaker
,
S. Grady
Handbook of Experimental Pharmacology
2009
Corpus ID: 19421860
The discovery that mammalian brain expresses the mRNAs for nine different nicotinic cholinergic receptor subunits (alpha2-alpha7…
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Highly Cited
2008
Highly Cited
2008
Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure
M. Doura
,
A. Gold
,
A. Keller
,
D. Perry
Brain Research
2008
Corpus ID: 11839667
2004
2004
Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro.
W. Deuther-Conrad
,
J. Patt
,
D. Feuerbach
,
F. Wegner
,
P. Brust
,
J. Steinbach
Il Farmaco
2004
Corpus ID: 31091520
Highly Cited
2000
Highly Cited
2000
Novel potent ligands for the central nicotinic acetylcholine receptor: synthesis, receptor binding, and 3D-QSAR analysis.
S. F. Nielsen
,
E. Nielsen
,
G. Olsen
,
T. Liljefors
,
D. Peters
Journal of Medicinal Chemistry
2000
Corpus ID: 24740069
In the past few years the focus on central acetylcholine receptors has shifted from compounds with affinity for muscarinic…
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Highly Cited
1998
Highly Cited
1998
Open-channel blockers at the human alpha4beta2 neuronal nicotinic acetylcholine receptor.
B. Buisson
,
D. Bertrand
Molecular Pharmacology
1998
Corpus ID: 19644392
To extend our knowledge of the pharmacological profile of human alpha4beta2 neuronal nicotinic receptors, we investigated the…
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Highly Cited
1997
Highly Cited
1997
Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca2+ Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors
A. Kuryatov
,
V. Gerzanich
,
Mark Nelson
,
F. Olale
,
J. Lindstrom
Journal of Neuroscience
1997
Corpus ID: 29429015
A mutation (S247F) in the channel-lining domain (M2) of the α4 nicotinic acetylcholine receptor (AChR) subunit has previously…
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Highly Cited
1997
Highly Cited
1997
Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes.
F. Olale
,
V. Gerzanich
,
A. Kuryatov
,
F. Wang
,
J. Lindstrom
Journal of Pharmacology and Experimental…
1997
Corpus ID: 12547150
Because chronic exposure to nicotine and nicotinic drugs might both activate and desensitize nicotinic acetylcholine receptors…
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