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nicotinate-nucleotide pyrophosphorylase (carboxylating) activity

Known as: QAPRTase activity, nicotinate-nucleotide diphosphorylase (carboxylating) activity, quinolinate phosphoribosyltransferase (decarboxylating) activity 
Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate. [EC:2.4… 
National Institutes of Health

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1991
1991
We measured the activities of the enzymes responsible for the metabolism of the excitotoxin quinolinic acid, 3…