nicotinamidase activity

Known as: NAMase activity, nicotinamide amidase activity, nicotinamide amidohydrolase activity 
Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3. [EC:3.5.1.19]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2016
01219552015

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Nicotinamidases catalyze the hydrolysis of nicotinamide to nicotinic acid and ammonia. Nicotinamidases are absent in mammals but… (More)
Is this relevant?
2008
2008
The nicotinamidase/pyrazinamidase (PncA) of Mycobacterium tuberculosis is involved in the activation of the important front-line… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 3
Is this relevant?
2007
2007
It has been suggested that nicotinamide must be degraded during germination; however, the enzyme responsible and its… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Borrelia burgdorferi, a spirochaete that causes Lyme borreliosis, contains 21 linear and circular plasmids thought to be… (More)
Is this relevant?
2002
2002
Nicotinamidase (NAMase) from the budding yeast, Saccharomyces cerevisiae, was purified by Ni(2+) affinity chromatography and gel… (More)
Is this relevant?
1999
1999
Pyrazinamide (PZA), an analog of nicotinamide, is a prodrug that requires conversion to the bactericidal compound pyrazinoic acid… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1996
1996
Pyrazinamide (PZA) is one of the three most important drugs for treatment of Mycobacterium tuberculosis infections. The… (More)
  • figure 1
  • table 1
  • table 2
Is this relevant?
1988
1988
A soluble enzyme which catalyzes the transfer of the methyl group from S-adenosyl-L-methionine to the nitrogen atom of pyridine-3… (More)
Is this relevant?
1987
1987
Nicotinamide deamidase (YNDase) has been purified from yeast through the use of a six-step procedure that includes molecular… (More)
  • table I
  • figure 8
  • figure 10
  • figure 9
Is this relevant?
1979
1979
Mutants of Salmonella typhimurium LT-2 deficient in nicotinamidase activity (pncA) or nicotinic acid phosphoribosyltransferase… (More)
Is this relevant?