Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

neurofibrillary tangle assembly

Known as: neurofibrillary tangle formation 
The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle. [GO_REF:0000079, GOC:sjp, GOC:TermGenie… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Brains of 42 individuals between the ages of 4 and 29 were examined with antibodies (AT8, 4G8) and silver stains for the presence… Expand
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Review
2007
Review
2007
Generation and deposition of amyloid beta peptides and neurofibrillary tangle formation are key mechanisms involved in AD… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Here, we describe the generation of a novel transgenic mouse model of human tauopathy. The rTg(tauP301L)4510 mouse expresses the… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Alzheimer's disease (AD) includes etiologically heterogeneous disorders characterized by senile or presenile dementia… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2004
Review
2004
The aberrant metabolism of tau and β-amyloid precursor protein (APP) has key roles in the neurodegenerative processes that… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The microtubule-binding protein tau has been implicated in the pathogenesis of Alzheimer's disease and related disorders. However… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Objective To determine initial locus and rate of degeneration of temporal lobe structures (total lobe, hippocampus and… Expand
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1995
Highly Cited
1995
ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual failure in aged humans. AD brains contain numerous… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
A central issue in the pathogenesis of Alzheimer's disease (AD) is the relationship between amyloid deposition and… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1992
Highly Cited
1992
We report the results of an examination of the elemental content of neurofibrillary tangle–bearing and neurofibrillary tangle… Expand
Is this relevant?