neural tube closure

The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. [GOC:dph, ISBN… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2017
0204019672017

Related topics

Related topics

3 relations

Broader (1)

Primary neurulation

Narrower (2)

anterior neural tube closureneuropore closure

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
neural tube closure
Primary neurulation
anterior neural tube closure
neuropore closure

Papers overview

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2011
2011
MIM regulates vertebrate neural tube closure.
Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although… (More)
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Highly Cited
2010
Highly Cited
2010
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell… (More)
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2010
2010
Dynamic imaging of mammalian neural tube closure.
Neurulation, the process of neural tube formation, is a complex morphogenetic event. In the mammalian embryo, an understanding of… (More)
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Highly Cited
2010
Highly Cited
2010
Local protease signaling contributes to neural tube closure in the mouse embryo.
We report an unexpected role for protease signaling in neural tube closure and the formation of the central nervous system. Mouse… (More)
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Highly Cited
2007
Highly Cited
2007
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure.
Planar-cell-polarity (PCP) signalling is necessary for initiation of neural tube closure in higher vertebrates. In mice with PCP… (More)
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2007
2007
Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure.
We explored the physiologic role of endothelial cell apoptosis during development by generating mouse embryos lacking the… (More)
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Highly Cited
2006
Highly Cited
2006
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells.
In the mouse, Frizzled3 (Fz3) and Frizzled6 (Fz6) have been shown previously to control axonal growth and guidance in the CNS and… (More)
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Highly Cited
2003
Highly Cited
2003
Shroom Induces Apical Constriction and Is Required for Hingepoint Formation during Neural Tube Closure
BACKGROUND The morphogenetic events of early vertebrate development generally involve the combined actions of several populations… (More)
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Highly Cited
2002
Highly Cited
2002
Sonic hedgehog and the molecular regulation of mouse neural tube closure.
Neural tube closure is a fundamental embryonic event whose molecular regulation is poorly understood. As mouse neurulation… (More)
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Highly Cited
1996
Highly Cited
1996
Loss of occludin and functional tight junctions, but not ZO-1, during neural tube closure--remodeling of the neuroepithelium prior to neurogenesis.
Neuroepithelial cells can generate nonepithelial cells, the neurons. Here we have investigated, for chick and mouse embryos, the… (More)
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