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neural tube closure

The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. [GOC:dph, ISBN… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Primary neurulation

Narrower (2)

anterior neural tube closureneuropore closure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell… Expand
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Highly Cited
2010
Highly Cited
2010
Local protease signaling contributes to neural tube closure in the mouse embryo.
We report an unexpected role for protease signaling in neural tube closure and the formation of the central nervous system. Mouse… Expand
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Highly Cited
2010
Highly Cited
2010
Dynamic imaging of mammalian neural tube closure.
Neurulation, the process of neural tube formation, is a complex morphogenetic event. In the mammalian embryo, an understanding of… Expand
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Highly Cited
2007
Highly Cited
2007
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure
Planar-cell-polarity (PCP) signalling is necessary for initiation of neural tube closure in higher vertebrates. In mice with PCP… Expand
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Review
2007
Review
2007
Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects.
BACKGROUND The number of mouse mutants and strains with neural tube closure defects (NTDs) now exceeds 190, including 155… Expand
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Highly Cited
2006
Highly Cited
2006
The Role of Frizzled3 and Frizzled6 in Neural Tube Closure and in the Planar Polarity of Inner-Ear Sensory Hair Cells
In the mouse, Frizzled3 (Fz3) and Frizzled6 (Fz6) have been shown previously to control axonal growth and guidance in the CNS and… Expand
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Highly Cited
2003
Highly Cited
2003
Shroom Induces Apical Constriction and Is Required for Hingepoint Formation during Neural Tube Closure
BACKGROUND The morphogenetic events of early vertebrate development generally involve the combined actions of several populations… Expand
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Review
2003
Review
2003
Epidemiology of neural tube defects.
Neural tube defects (NTDs)-malformations secondary to abnormal neural tube closure between the third and fourth weeks of… Expand
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Highly Cited
1996
Highly Cited
1996
Loss of occludin and functional tight junctions, but not ZO-1, during neural tube closure--remodeling of the neuroepithelium prior to neurogenesis.
Neuroepithelial cells can generate nonepithelial cells, the neurons. Here we have investigated, for chick and mouse embryos, the… Expand
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Review
1993
Review
1993
Neural tube defects
Neural tube defects (NTDs), including spina bifida and anencephaly are severe birth defects of the central nervous system that… Expand
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