nephrocyte diaphragm

A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte… (More)
National Institutes of Health

Papers overview

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2018
2018
Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes
Insect nephrocytes provide a valuable model for kidney disease, as they are structurally and functionally homologous to mammalian… (More)
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Review
2014
Review
2014
A brief overview on IRM function across evolution.
The description of the Rst protein by Karl-Friedrich Fischbach and colleagues was a milestone in the discovery of the irre cell… (More)
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2013
2013
An in vivo functional analysis system for renal gene discovery in Drosophila pericardial nephrocytes.
The difficulty in accessing mammalian nephrons in vivo hinders the study of podocyte biology. The Drosophila nephrocyte shares… (More)
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Review
2011
Review
2011
The Drosophila nephrocyte.
PURPOSE OF REVIEW The functioning kidney requires proper organization in multiple cell types that mediate filtration and removal… (More)
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Highly Cited
2009
Highly Cited
2009
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm
The nephron is the basic structural and functional unit of the vertebrate kidney. It is composed of a glomerulus, the site of… (More)
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Highly Cited
2009
Highly Cited
2009
Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes.
The Immunoglobulin superfamily (IgSF) proteins Neph1 and Nephrin are co-expressed within podocytes in the kidney glomerulus… (More)
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