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nephrocyte diaphragm

A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Nephrin Signaling Results in Integrin β1 Activation.
BACKGROUND Patients with certain mutations in the gene encoding the slit diaphragm protein Nephrin fail to develop functional… 
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2018
2018
Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes
&NA; Insect nephrocytes provide a valuable model for kidney disease, as they are structurally and functionally homologous to… 
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Review
2014
Review
2014
A Brief Overview on IRM Function Across Evolution
Abstract The description of the Rst protein by Karl-Friedrich Fischbach and colleagues was a milestone in the discovery of the… 
Highly Cited
2013
Highly Cited
2013
An in vivo functional analysis system for renal gene discovery in Drosophila pericardial nephrocytes.
The difficulty in accessing mammalian nephrons in vivo hinders the study of podocyte biology. The Drosophila nephrocyte shares… 
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Review
2011
Review
2011
The Drosophila nephrocyte
  • R. Cagan
  • Current opinion in nephrology and hypertension
  • 2011
  • Corpus ID: 33715372
Purpose of review The functioning kidney requires proper organization in multiple cell types that mediate filtration and removal… 
Highly Cited
2009
Highly Cited
2009
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm
The nephron is the basic structural and functional unit of the vertebrate kidney. It is composed of a glomerulus, the site of… 
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Highly Cited
2009
Highly Cited
2009
Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes
The Immunoglobulin superfamily (IgSF) proteins Neph1 and Nephrin are co-expressed within podocytes in the kidney glomerulus… 
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