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nelotanserin
Known as:
1-(3-(4-Bromo-1-Methyl-1H-Pyrazol-5-yl)-4-Methoxyphenyl)-3-(2,4-Difluorophenyl)Urea
, Urea, N-(3-(4-Bromo-1-Methyl-1H-Pyrazol-5-yl)-4-Methoxyphenyl)-N'-(2,4-Difluorophenyl)-
National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
APD125
Broader (2)
Phenylurea Compounds
Pyrazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The Involvement of 5-HT 2A Receptor in the Regulation of Sleep and Wakefulness, and the Potential Therapeutic Use of Selective 5-HT 2A Receptor Antagonists and Inverse Agonists for the Treatment of…
J. Monti
,
S. Perumal
,
D. Spence
,
P. Torterolo
2018
Corpus ID: 79927377
Several agents have been shown to improve sleep induction and/or maintenance in patients with primary or comorbid insomnia. These…
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2018
2018
Serotonin Receptor Inverse Agonists or Antagonists for Use in Reducing Amyloid-Beta Peptides and Accumulation
H. Mucke
2018
Corpus ID: 207785412
Several approaches that are directed against amyloid plaque deposition, or against the formation of amyloid precursor protein…
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Review
2017
Review
2017
A Phase 2 Study of Nelotanserin, a Novel 5HT2A Receptor Inverse Agonist, in Dementia with Lewy Bodies and Parkinson’s Disease Dementia Subjects Experiencing Visual Hallucinations (P6.088)
W. Wen
,
S. Ramaswamy
,
Kunal S. Kishnani
,
G. Ramaswamy
,
L. Friedhoff
Neurology
2017
Corpus ID: 80597987
Objective: To evaluate the safety and efficacy of nelotanserin in Lewy body dementia subjects experiencing visual hallucinations…
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Review
2017
Review
2017
Selective Serotonin 5-HT2A Receptor Antagonists and Inverse Agonists Specifically Promote Slow Wave Sleep (Stage N3) in Man
J. Monti
,
P. Torterolo
,
D. Spence
,
S. Pandi‑Perumal
Sleep and Vigilance
2017
Corpus ID: 80081065
Several drug classes are widely prescribed when difficulties with sleep induction or sleep maintenance occur, as is the case in…
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