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negative regulation of transforming growth factor beta1 activation

Known as: negative regulation of TGFbeta 1 activation, down-regulation of TGFbeta 1 activation, downregulation of transforming growth factor beta1 activation 
Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation. [GOC:sl, GOC:TermGenie]
National Institutes of Health

Related topics

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2 relations

Broader (1)

biological control
transforming growth factor beta1 activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Differential effects of histone deacetylase inhibitors on phorbol ester‐ and TGF‐β1 induced murine tissue inhibitor of metalloproteinases‐1 gene expression
Expression of the tissue inhibitor of metalloproteinases‐1 (Timp‐1) gene can be induced by either phorbol myristate acetate (PMA… 
2003
2003
Transforming Growth Factor-1 Decreases Expression of the Epithelial Sodium Channel ENaC and Alveolar Epithelial Vectorial Sodium and Fluid Transport via an ERK 1 / 2-dependent Mechanism *
  • 2003
  • Corpus ID: 30919977
From the §Laboratory of Surgical Research, Cardiovascular Research Institute, Lung Biology Center, Departments of Anesthesia… 
Highly Cited
2001
Highly Cited
2001
Reduced Smad3 protein expression and altered transforming growth factor-beta1-mediated signaling in cystic fibrosis epithelial cells.
Cystic fibrosis (CF) is a disease characterized by an aggressive inflammatory response in the airways. Given the antiinflammatory… 
2000
2000
Kinetics of expression of connective tissue growth factor gene during liver regeneration after partial hepatectomy and D-galactosamine-induced liver injury in rats.
Connective tissue growth factor (CTGF) is up-regulated by TGF-beta1 during wound healing. The present study examined the… 
Highly Cited
1999
Highly Cited
1999
Transforming growth factor-beta1 polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through a monocyte/macrophage differentiation pathway.
We have recently demonstrated that CD11b-/dullCD11c+ and CD11b+hiCD11c+ dendritic cell (DC) precursor subsets represent two… 
1999
1999
Abnormalities of extracellular matrices and transforming growth factor beta1 localization in the kidney of the hereditary nephrotic mice (ICGN strain).
ICR-derived strain with glomerulonephritis (ICGN) is a strain of mice with hereditary nephrotic syndrome with an unidentified… 
Highly Cited
1997
Highly Cited
1997
Down-regulation of the Cyclin A Promoter by Transforming Growth Factor-β1 Is Associated with a Reduction in Phosphorylated Activating Transcription Factor-1 and Cyclic AMP-responsive Element-binding…
Transforming growth factor (TGF)-β1 prevents cell cycle progression by inhibiting several regulators, including cyclin A. To… 
1997
1997
Immunohistochemical study of TGF-alpha, TGF-beta1, EGFR, and IGF-1 expression in human breast carcinoma.
Localization of growth factors such as transforming growth factor alpha (TGF-alpha) and beta1 (TGF-beta1), insulin-like growth… 
1997
1997
In vivo transfer of engineered macrophages into the glomerulus: endogenous TGF-beta-mediated defense against macrophage-induced glomerular cell activation.
Communication between resident glomerular cells and infiltrating macrophages plays a crucial role in the pathogenesis of… 
Highly Cited
1996
Highly Cited
1996
Transforming growth factor-beta1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP.
LNCaP is an androgen-responsive prostatic cancer cell line that exhibits a bell-shaped growth response to increasing doses of… 
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