negative regulation of telosome assembly
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A significant fraction (∼10%) of cancer cells maintain their telomere length via a telomerase-independent mechanism known as… Expand The roles of protection of telomeres 1 (POT1) in human ovarian cancer have not been fully elucidated. Here, we investigated the… Expand The shelterin proteins play important roles in telomere maintenance and genome stability. These proteins have been found to be… Expand Mammalian shelterin proteins POT1 and TPP1 form a stable heterodimer that protects chromosome ends and regulates telomerase… Expand A pot culture experiment was carried out to study response of Farm Yard Manure (FYM), nitrogen, phosphorus and potassium levels… Expand Cells of B-cell chronic lymphocytic leukemia (B-CLL) are characterized by short telomeres despite a low proliferative index… Expand