negative regulation of small GTPase mediated signal transduction

Known as: down regulation of small GTPase mediated signal transduction, downregulation of small GTPase mediated signal transduction, negative regulation of small GTPase-mediated signal transduction 
Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2014
02420032014

Papers overview

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2015
2015
The small GTPase Rab27a has been shown to control membrane trafficking and microvesicle transport pathways, in particular the… (More)
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2014
2014
Aberrations of Notch signaling have been implicated in a variety of human cancers. Oncogenic mutations in NOTCH1 are common in… (More)
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2009
2009
Protein synthesis is a highly conserved process in all living cells involving several members of the translation factor (TRAFAC… (More)
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2008
2008
Pulmonary vascular remodeling is commonly associated with pulmonary hypertension and is characterized by media thickening and… (More)
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2008
2008
Epithelial cell migration is a complex process crucial for embryonic development, wound healing and tumor metastasis. It depends… (More)
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2008
2008
The GTPase RhoA is a downstream target of heterotrimeric G(13) proteins and plays key roles in cell migration and invasion. Here… (More)
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2007
2007
In normal epithelial cells, cell-matrix interaction is required for cell survival and proliferation, whereas disruption of this… (More)
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2006
2006
In this paper the essential GTPase YlqF is shown to participate in the biogenesis of the 50S ribosomal subunit in Bacillus… (More)
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Highly Cited
2004
Highly Cited
2004
The small GTPase Rap is best characterized as a critical regulator of integrin-mediated cell adhesion, although its mechanism of… (More)
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2003
2003
The novel Ras-like small GTPase Rin is expressed prominently in adult neurons, and binds calmodulin (CaM) through its COOH… (More)
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