negative regulation of purine nucleotide biosynthetic process

Known as: down regulation of purine nucleotide synthesis, down regulation of purine nucleotide biosynthetic process, downregulation of purine nucleotide anabolism 
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. [GOC:go_curators, GOC… (More)
National Institutes of Health

Papers overview

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2012
2012
Purine nucleotides are either synthesized de novo from 5-phosphoribosyl-1-pyrophosphate (PRPP) or salvaged from the environment… (More)
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2011
2011
The cyclic purine nucleotides cAMP and cGMP are well-characterized second messengers and activators of PKA and PKG, respectively… (More)
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Review
2006
Review
2006
In human and rodent cells, MTH1, an oxidized purine nucleoside triphosphatase, efficiently hydrolyzes oxidized dGTP, GTP, dATP… (More)
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2006
2006
Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. It is capable of… (More)
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2005
2005
Plasmodium falciparum is unable to synthesize purine bases and relies upon purine salvage and purine recycling to meet its purine… (More)
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Highly Cited
2003
Highly Cited
2003
DNA microarrays provide a global view of the physiological state of the cell by parallel analysis of the expression levels of all… (More)
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1994
1994
Breast milk contains nucleotide salts that are only present in minimal amounts in modern infant formulas prepared from cows' milk… (More)
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1982
1982
The isolation of the purine nucleotide binding protein (NbP), the putative uncoupling protein, from hamster brown adipose tissue… (More)
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1972
1972
Geometric and position isomers of zeatin and of ribosylzeatin and other compounds closely related to zeatin have been tested in… (More)
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