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negative regulation of protein monoubiquitination

Known as: down regulation of protein monoubiquitinylation, down-regulation of protein monoubiquitination, downregulation of protein monoubiquitinylation 
Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination. [GOC:TermGenie, PMID:21931591]
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
protein monoubiquitination

Papers overview

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2018
2018
Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling
Cullin-RING E3 ubiquitin ligases (CRLs) are large and diverse multisubunit protein complexes that contribute to about one-fifth… Expand
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2016
2016
H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs.
Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in embryonic stem cells (ESCs) to regulate… Expand
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2015
2015
Rpn10 monoubiquitination orchestrates the association of the ubiquilin-type DSK2 receptor with the proteasome.
Despite the progress made in understanding the roles of proteasome polyubiquitin receptors, such as the subunits Rpn10… Expand
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Highly Cited
2012
Highly Cited
2012
CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis.
We reported that Cullin4B-Ring E3 ligase complex (CRL4B) is physically associated with Polycomb-repressive complex 2 (PRC2). We… Expand
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Highly Cited
2012
Highly Cited
2012
DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI
FANCI and FANCD2 form a complex, and play essential roles in the repair of interstrand DNA crosslinks (ICLs) by the Fanconi… Expand
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2012
2012
Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor
Fanconi anemia (FA) is a rare disease characterized by congenital defects, progressive bone marrow failure and heightened cancer… Expand
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Highly Cited
2010
Highly Cited
2010
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
As part of the genotoxic stress response, cells activate the transcription factor NF-κB. The DNA strand break sensor poly(ADP… Expand
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Highly Cited
2009
Highly Cited
2009
Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1
Histone H2B monoubiquitination by Rad6/Bre1 is required for the trimethylation of both histone H3K4 and H3K79 by COMPASS and Dot1… Expand
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2009
2009
Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis.
According to a recent IARC Working Group report, alcohol consumption is causally related to an increased risk of cancer of the… Expand
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2007
2007
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.
The Fanconi anemia (FA) nuclear core complex and the E2 ubiquitin-conjugating enzyme UBE2T are required for the S phase and DNA… Expand
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