negative regulation of prostaglandin-E synthase activity
Known as: negative regulation of PGE isomerase activity, negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity, negative regulation of prostaglandin-H2 E-isomerase activity
Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity. [GOC:BHF]