negative regulation of neurofibrillary tangle assembly

Known as: down regulation of neurofibrillary tangle assembly, down regulation of neurofibrillary tangle formation, down-regulation of neurofibrillary tangle formation 
Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly. [GO_REF:0000058, GOC:sjp, GOC:TermGenie… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
051019732017

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Review
2016
Review
2016
Alzheimer's disease (AD) is an age-associated neurodegenerative amyloid disease and is considered a social and clinical problem… (More)
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Highly Cited
2012
Highly Cited
2012
Neurofibrillary tangles advance from layer II of the entorhinal cortex (EC-II) toward limbic and association cortices as… (More)
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Highly Cited
2003
Highly Cited
2003
The principal pathological features of Alzheimer's disease (AD) are extracellular amyloid plaques and intracellular… (More)
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Highly Cited
2003
Highly Cited
2003
Molecular chaperones and their functions in protein folding have been implicated in several neurodegenerative diseases, including… (More)
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Highly Cited
2000
Highly Cited
2000
3F4, a monoclonal antibody raised against partially purified paired helical filaments (PHFs), strongly labeled neurofibrillary… (More)
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Highly Cited
1998
Highly Cited
1998
Previous studies have implicated the failure to degrade aggregated Abeta1-42 in late endosomes or secondary lysosomes as a… (More)
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Highly Cited
1996
Highly Cited
1996
The two pathological lesions found in the brains of Alzheimer's disease patients, neurofibrillary tangles and neuritic plaques… (More)
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Highly Cited
1995
Highly Cited
1995
One of the hallmarks of Alzheimer disease is the pathological aggregation of tau protein into paired helical filaments (PHFs) and… (More)
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Highly Cited
1995
Highly Cited
1995
Niemann-Pick disease type C (NPC) is an autosomal recessive disease, belonging to a clinically heterogeneous group of lipid… (More)
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Highly Cited
1986
Highly Cited
1986
The relationship of the neurofibrillary tangle, found in Alzheimer disease and aged brains, to normal or abnormal cytoskeletal… (More)
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