negative regulation of mitotic cell cycle DNA replication

Known as: negative regulation of DNA replication involved in S phase involved in mitotic cell cycle, down regulation of DNA replication involved in S-phase involved in mitotic cell cycle, down-regulation of DNA replication involved in S phase involved in mitotic cell cycle 
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication. [GO_REF:0000058, GOC:mtg_cell_cycle… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Telomere shortening and disruption of telomeric components are pathways that induce telomere deprotection. Here we describe… (More)
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Highly Cited
2010
Highly Cited
2010
Previously, we proposed a new model for understanding the "Warburg effect" in tumor metabolism. In this scheme, cancer-associated… (More)
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Highly Cited
2009
Highly Cited
2009
Here, we propose a new model for understanding the Warburg effect in tumor metabolism. Our hypothesis is that epithelial cancer… (More)
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Highly Cited
2005
Highly Cited
2005
Several mitochondrial proteins are tumor suppressors. These include succinate dehydrogenase (SDH) and fumarate hydratase, both… (More)
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Highly Cited
2005
Highly Cited
2005
The polo-like kinase Plk4 (also called Sak) is required for late mitotic progression, cell survival and postgastrulation… (More)
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Highly Cited
2004
Highly Cited
2004
Early mitotic inhibitor 1 (Emi1) inhibits the activity of the anaphase promoting complex/cyclosome (APC/C), which is a… (More)
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Highly Cited
2000
Highly Cited
2000
In Xenopus development, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. CPEB and maskin… (More)
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Highly Cited
1999
Highly Cited
1999
During a normal cell cycle, entry into S phase is dependent on completion of mitosis and subsequent activation of cyclin… (More)
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Highly Cited
1997
Highly Cited
1997
Proper orientation of the mitotic spindle is critical for successful cell division in budding yeast. To investigate the mechanism… (More)
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Highly Cited
1989
Highly Cited
1989
I have synthesized a novel derivative of carboxyfluorescein that is nonfluorescent, but can be converted to a fluorescent form by… (More)
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