negative regulation of mitotic DNA replication initiation

Known as: down regulation of DNA replication initiation involved in mitotic DNA replication, downregulation of DNA replication initiation involved in mitotic DNA replication, downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication 
Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. [GO_REF… (More)
National Institutes of Health

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Broader (1)

biological control

Papers overview

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Highly Cited
2013
Highly Cited
2013
The Control Region of Mitochondrial DNA Shows an Unusual CpG and Non-CpG Methylation Pattern
DNA methylation is a common epigenetic modification of the mammalian genome. Conflicting data regarding the possible presence of… (More)
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Highly Cited
2011
Highly Cited
2011
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Breast cancer suppressor BRCA2 is critical for maintenance of genomic integrity and resistance to agents that damage DNA or… (More)
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Highly Cited
2010
Highly Cited
2010
The role of mitochondrial DNA copy number in mammalian fertility.
Mammalian mitochondrial DNA (mtDNA) is a small, maternally inherited genome that codes for 13 essential proteins in the… (More)
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Highly Cited
2006
Highly Cited
2006
Deregulated Replication Licensing Causes DNA Fragmentation Consistent with Head-to-Tail Fork Collision
Correct regulation of the replication licensing system ensures that no DNA is rereplicated in a single cell cycle. When the… (More)
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Highly Cited
2005
Highly Cited
2005
Specific binding of tombusvirus replication protein p33 to an internal replication element in the viral RNA is essential for replication.
The mechanism of template selection for genome replication in plus-strand RNA viruses is poorly understood. Using the… (More)
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Highly Cited
2004
Highly Cited
2004
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery.
Herpes simplex virus 1 (HSV-1) forms replication compartments (RCs), domains in which viral DNA replication, late-gene… (More)
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Highly Cited
2003
Highly Cited
2003
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles.
Hepatitis B virus (HBV) includes an X gene (HBx gene) that plays a critical role in liver carcinogenesis. Because centrosome… (More)
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Highly Cited
2003
Highly Cited
2003
Animal mitochondrial DNA recombination revisited
Exchange of homologous sequences between mitochondrial DNA (mtDNA) molecules is thought to be absent in animals, primarily… (More)
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Highly Cited
2003
Highly Cited
2003
Evidence for a two membrane–spanning autonomous mitochondrial DNA replisome
The unit of inheritance for mitochondrial DNA (mtDNA) is a complex nucleoprotein structure termed the nucleoid. The organization… (More)
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Highly Cited
2000
Highly Cited
2000
Coupled Leading- and Lagging-Strand Synthesis of Mammalian Mitochondrial DNA
Analysis of mammalian mtDNA by two-dimensional agarose gel electrophoresis revealed two classes of replication intermediate. One… (More)
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