FAQ

negative regulation of interleukin-2 secretion

Known as: down-regulation of IL-2 secretion, inhibition of IL-2 secretion, downregulation of IL-2 secretion 
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2 secretion. [GOC:TermGenie, GOC:yaf]

Topic mentions per year

Topic mentions per year

1988-2016
012319882016

Related topics

Related topics

2 relations

Broader (1)

biological control
interleukin-2 secretion

Related mentions per year

Related mentions per year

1940-2018
19401960198020002020
negative regulation of interleukin-2 secretion
biological control
interleukin-2 secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing.
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress-activated transcription factor activated by stimuli such as… (More)
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2017
2017
JPET #238899 1 Nrf2-dependent and –independent effects of tBHQ, CDDO-Im, and H2O2 in human Jurkat T cells as determined by CRISPR/Cas9 gene editing
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress activated transcription factor, activated by stimuli such as… (More)
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2008
2008
A COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl glycerol, mediates suppression of IL-2 secretion in activated Jurkat T cells.
Previous studies from this laboratory have demonstrated that a COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl… (More)
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2006
2006
Sodium arsenite-induced inhibition of cell proliferation is related to inhibition of IL-2 mRNA expression in mouse activated T cells
A proposed mechanism for the As-induced inhibition of cell proliferation is the inhibition of IL-2 secretion. However, the… (More)
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2000
2000
Cutting edge: tyrosine-independent transmission of inhibitory signals by CTLA-4.
CTLA-4 is an important inhibitor of T cell activation. We used Jurkat cells expressing mutants of murine CTLA-4 to study the… (More)
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Highly Cited
2000
Highly Cited
2000
The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses.
The peroxisome proliferator-activated receptors (PPARs) are a family of transcription factors belonging to the nuclear receptor… (More)
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1999
1999
Cannabinol-Mediated Inhibition of Nuclear Factor-kB, cAMP Response Element-Binding Protein, and Interleukin-2 Secretion by Activated Thymocytes
Cannabinol (CBN), an immunosuppressive cannabinoid and ligand for the peripheral cannabinoid receptor CB2, inhibits the cAMP… (More)
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1996
1996
Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas.
The functional role of reactive oxygen intermediates (ROI) in activation-induced death of mature T lymphocytes and hybridomas was… (More)
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1996
1996
Collaboration of TCR-, CD4- and CD28-mediated signalling in antigen-specific MHC class II-restricted T-cells.
A previously developed experimental system was applied to obtain qualitative and quantitative data on the contribution of TCR… (More)
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1994
1994
Corneal endothelial cells inhibit T cell proliferation by blocking IL-2 production.
We have reported that Ia+ LEW rat corneal endothelial (CE) cells could not induce Ag-specific proliferation of MHC compatible T… (More)
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