negative regulation of hypoxia-inducible factor-1alpha signaling pathway

Known as: downregulation of hypoxia-inducible factor-1alpha signalling pathway, down-regulation of hypoxia-inducible factor-1alpha signaling pathway, downregulation of HIF1alpha pathway 
Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. [GOC:bf, GOC… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Hypoxia induces the expansion of glioblastoma stem cells (GSCs), but the mechanism underlying it is still unclear. Here, we… (More)
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Review
2010
Review
2010
Hypoxia inducible factors (HIFs) regulate a variety of genes to prepare cells to adapt and survive under a hypoxic environment… (More)
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Review
2010
Review
2010
Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The goals of the present study were to investigate the mechanism of hypoxia-mediated chemoresistance in liver cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays a critical role in angiogenesis, survival, metastasis… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor, consisting of an alpha subunit and a beta subunit, that… (More)
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Highly Cited
2005
Highly Cited
2005
We have recently identified a mechanistic link between disruption of the microtubule cytoskeleton and inhibition of tumor… (More)
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Review
2004
Review
2004
Structural and functional integrity of brain function profoundly depends on a regular oxygen and glucose supply. Any disturbance… (More)
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Highly Cited
2003
Highly Cited
2003
When oxygen becomes limiting, cells shift primarily to a glycolytic mode for generation of energy. A key regulator of glycolytic… (More)
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2001
2001
Hypoxia-inducible factor 1alpha (HIF1alpha) plays a pivotal role in embryogenesis, angiogenesis, and tumorigenesis. HIF1alpha… (More)
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