negative regulation of hydrolase activity

Known as: hydrolase inhibitor, downregulation of hydrolase activity, down regulation of hydrolase activity 
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. [GOC:ai]
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The endogenous cannabinoid (endocannabinoid) anandamide is principally degraded by the integral membrane enzyme fatty acid amide… (More)
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2009
2009
A long-loop pathway, involving the hypothalamic arcuate nucleus (ARC), ventrolateral periaqueductal gray (vlPAG), and the rostral… (More)
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2008
2008
Microglial cell activation and migration play an important role in neuroinflammation propagation. While it is known that the… (More)
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Highly Cited
2007
Highly Cited
2007
Fatty acid amide hydrolase (FAAH) is an intracellular serine hydrolase that catalyzes the cleavage of bioactive fatty acid… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND PURPOSE N-arachidonoyl-serotonin (AA-5-HT) is an inhibitor of fatty acid amide hydrolase (FAAH)-catalysed… (More)
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Highly Cited
2005
Highly Cited
2005
Fatty acid amide hydrolase (FAAH) is an intracellular serine enzyme that catalyzes the hydrolysis of bioactive fatty acid… (More)
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Highly Cited
2005
Highly Cited
2005
Changes in the lungs due to smoking include inflammation, epithelial damage, and remodeling of the airways. Airway inflammation… (More)
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Highly Cited
2005
Highly Cited
2005
The present study tested the hypothesis that increasing epoxyeicosatrienoic acids by inhibition of soluble epoxide hydrolase (sEH… (More)
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Highly Cited
2004
Highly Cited
2004
Activation of the hypothalamic-pituitary-adrenal (HPA) axis is critical for the adaptation and survival of animals upon exposure… (More)
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