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negative regulation of heterochromatin assembly

Known as: negative regulation of heterochromatin formation, down-regulation of heterochromatin formation, down regulation of heterochromatin formation 
Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. [GOC:mah]
National Institutes of Health

Related topics

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2 relations

Broader (1)

biological control
heterochromatin assembly

Papers overview

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2018
2018
Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We… Expand
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2016
2016
The proper connection between shelterin components is required for telomeric heterochromatin assembly.
Telomeric regions contain prominent sites of heterochromatin, which is associated with unique histone modification profiles such… Expand
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Highly Cited
2015
Highly Cited
2015
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
Werner syndrome (WS) is a premature aging disorder caused by WRN protein deficiency. Here, we report on the generation of a human… Expand
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2013
2013
Chromatin remodeling, BRCA1, SAHF and cellular senescence
Cellular senescence is a state of stable cell growth arrest. Activation of oncogenes in primary mammalian cells typically… Expand
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2013
2013
The Deacetylase Sir2 from the Yeast Clavispora lusitaniae Lacks the Evolutionarily Conserved Capacity to Generate Subtelomeric Heterochromatin
Deacetylases of the Sir2 or sirtuin family are thought to regulate life cycle progression and life span in response to nutrient… Expand
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2012
2012
Association of the interferon-b gene with pericentromeric heterochromatin is dynamically regulated during virus infection through a YY 1-dependent mechanism
Nuclear architecture as well as gene nuclear positioning can modulate gene expression. In this work, we have analyzed the nuclear… Expand
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2011
2011
The Role of Histone Modifications in Telomere Elongation and Epigenetic Gene Switching at Subtelomeric Heterochromatin in Saccharomyces cerevisiae
 
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2008
2008
The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin.
Heterochromatic chromosomal regions undergo large-scale reorganization and progressively aggregate, forming chromocenters. These… Expand
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2004
2004
Redundant roles for histone H3 N-terminal lysine residues in subtelomeric gene repression in Saccharomyces cerevisiae.
The transcription of genes located in subtelomeric regions of yeast chromosomes is repressed relative to the rest of the genome… Expand
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2002
2002
Genetic remodeling and transcriptional remodeling of subtelomeric heterochromatin are different.
The structure, the extension, and the regulatory functions of telomeric and subtelomeric heterochromatin are not completely… Expand
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