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negative regulation of guanyl-nucleotide exchange factor activity

Known as: downregulation of guanyl-nucleotide release factor activity, downregulation of GDS, down regulation of guanyl-nucleotide exchange factor activity 
Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity. [GO_REF:0000059, GOC… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Summary: A genetic knockout of a pollen-expressed cyclic nucleotide-gated ion channel (cngc16) provides evidence for a signaling… Expand
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Highly Cited
2008
Highly Cited
2008
Rho of plants (ROP) proteins, also known as RAC proteins, are Rho-related GTPases that function as molecular switches in a… Expand
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Highly Cited
2001
Highly Cited
2001
RasGRP represents the prototype of a new class of guanine nucleotide exchange factors that activate small GTPases. The guanyl… Expand
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Highly Cited
1992
Highly Cited
1992
The recently characterized corticosteroid receptor on amphibian neuronal membranes appears to mediate rapid, stress-induced… Expand
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Highly Cited
1990
Highly Cited
1990
The selectivity of D2 dopamine receptor-guanine nucleotide-binding protein (G protein) coupling was studied by reconstitution… Expand
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Highly Cited
1989
Highly Cited
1989
Pseudomonas aeruginosa exoenzyme S has appeared to be relatively indiscriminate in its choice of substrates, but in fact it ADP… Expand
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Review
1988
Review
1988
  • J. Moss, M. Vaughan
  • Advances in enzymology and related areas of…
  • 1988
  • Corpus ID: 10810659
 
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Highly Cited
1978
Highly Cited
1978
Treatment of pigeon erythrocyte membranes with cholera toxin and NAD(+) enhanced the GTP stimulation and suppressed the F… Expand
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Highly Cited
1977
Highly Cited
1977
Treatment of turkey erthrocyte membranes with cholera toxin caused an enhancement of the basal and catecholamine-stimulated… Expand
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Highly Cited
1975
Highly Cited
1975
  • J. Orly, M. Schramm
  • Proceedings of the National Academy of Sciences…
  • 1975
  • Corpus ID: 38849998
Activation of the adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1[ from turkey erythrocytes by isoproterenol… Expand
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