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negative regulation of germinal center formation
Known as:
down regulation of germinal center formation
, down-regulation of germinal center formation
, downregulation of germinal center formation
Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. [GOC:add]
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
biological control
germinal center formation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice
Audur Anna Aradottir Pind
,
M. Dubik
,
+6 authors
Stefania P. Bjarnarson
Frontiers in Immunology
2019
Corpus ID: 202759697
Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited…
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Review
2018
Review
2018
The Transcriptional Regulation of Germinal Center Formation
Shuang Song
,
P. Matthias
Frontiers in Immunology
2018
Corpus ID: 52155772
Germinal centers (GCs) are essential structures of the humoral immune response, which form in the periphery in response to T cell…
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2018
2018
B Cell–Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle
Meijie Tian
,
Zhaolin Hua
,
+9 authors
B. Hou
Journal of Immunology
2018
Corpus ID: 207435669
Although TLR signaling in B cells has been implicated in the germinal center (GC) responses during viral infections and…
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Highly Cited
2017
Highly Cited
2017
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
Jonatan Ersching
,
A. Efeyan
,
+6 authors
G. Victora
Immunity
2017
Corpus ID: 205426908
Highly Cited
2015
Highly Cited
2015
The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.
D. Dominguez-Sola
,
J. Kung
,
+4 authors
R. Dalla-Favera
Immunity
2015
Corpus ID: 5260389
2015
2015
TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation
X. Ci
,
M. Kuraoka
,
+8 authors
X. Zhong
PLoS ONE
2015
Corpus ID: 17238577
Accumulating evidence indicates that the tuberous sclerosis complex 1 (TSC1), a tumor suppressor that acts by inhibiting mTOR…
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Review
2014
Review
2014
Evaluation of Germinal Center-like Structures and B Cell Clonality in Patients with Primary Sjögren Syndrome with and without Lymphoma
S. J. Johnsen
,
E. Berget
,
M. Jonsson
,
L. Helgeland
,
R. Omdal
,
R. Jonsson
Journal of Rheumatology
2014
Corpus ID: 207602152
Objective. Germinal center (GC)-like structures have previously been observed in minor salivary glands (MSG) of patients with…
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1998
1998
Gap-Junction Communication Pathways in Germinal Center Reactions
T. Krenács
,
M. Rosendaal
Developmental Immunology
1998
Corpus ID: 1918220
Intercellular channels called gap junctions enable multicellular organisms to exchange information rapidly between cells. Though…
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Highly Cited
1997
Highly Cited
1997
Paracrine Regulation of Germinal Center B Cell Adhesion through the c-Met–Hepatocyte Growth Factor/Scatter Factor Pathway
R. van der Voort
,
T. Taher
,
R. Keehnen
,
L. Smit
,
M. Groenink
,
S. Pals
Journal of Experimental Medicine
1997
Corpus ID: 980998
T cell–dependent humoral immune responses are initiated by the activation of naive B cells in the T cell areas of the secondary…
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Highly Cited
1997
Highly Cited
1997
Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells.
A. Walker
,
S. T. Taylor
,
J. Hickman
,
C. Dive
Cancer Research
1997
Corpus ID: 1420340
Bcl-2 suppresses drug-induced apoptosis in vitro, although in many cases, this results only in a delayed onset of cell death. In…
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