FAQ

negative regulation of germinal center formation

Known as: down regulation of germinal center formation, down-regulation of germinal center formation, downregulation of germinal center formation 
Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. [GOC:add]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2017
01219652017

Related topics

Related topics

2 relations

Broader (1)

biological control
germinal center formation

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
negative regulation of germinal center formation
biological control
germinal center formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle.
Although TLR signaling in B cells has been implicated in the germinal center (GC) responses during viral infections and… (More)
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2017
2017
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase.
During antibody affinity maturation, germinal center (GC) B cells cycle between affinity-driven selection in the light zone (LZ… (More)
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2015
2015
The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.
The pathways regulating formation of the germinal center (GC) dark zone (DZ) and light zone (LZ) are unknown. In this study we… (More)
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2015
2015
TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation
Accumulating evidence indicates that the tuberous sclerosis complex 1 (TSC1), a tumor suppressor that acts by inhibiting mTOR… (More)
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2015
2015
This information is current as Germinal Center B Cells Hypersensitivity Distinguishes Human Cutting Edge : Redox Signaling
 
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Review
2014
Review
2014
Evaluation of germinal center-like structures and B cell clonality in patients with primary Sjögren syndrome with and without lymphoma.
OBJECTIVE Germinal center (GC)-like structures have previously been observed in minor salivary glands (MSG) of patients with… (More)
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1998
1998
Gap-Junction Communication Pathways in Germinal Center Reactions
Intercellular channels called gap junctions enable multicellular organisms to exchange information rapidly between cells. Though… (More)
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Highly Cited
1997
Highly Cited
1997
Paracrine Regulation of Germinal Center B Cell Adhesion through the c-Met–Hepatocyte Growth Factor/Scatter Factor Pathway
T cell-dependent humoral immune responses are initiated by the activation of naive B cells in the T cell areas of the secondary… (More)
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1997
1997
Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells.
Bcl-2 suppresses drug-induced apoptosis in vitro, although in many cases, this results only in a delayed onset of cell death. In… (More)
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1965
1965
Germinal Center Changes and Plasma Cell Reaction during the Primary Immune Response.
 
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