FAQ

negative regulation of exoribonuclease activity

Known as: down regulation of exoribonuclease activity, down-regulation of exoribonuclease activity, downregulation of exoribonuclease activity 
Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity. [GOC:TermGenie, PMID:22570495]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
01219802018

Related topics

Related topics

2 relations

Broader (1)

biological control
exoribonuclease activity

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
negative regulation of exoribonuclease activity
biological control
exoribonuclease activity

Papers overview

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2018
2018
Mbf1 ensures Polycomb silencing by protecting E(z) mRNA from degradation by Pacman
Under stress conditions, the coactivator Multiprotein bridging factor 1 (Mbf1) translocates from the cytoplasm into the nucleus… (More)
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2015
2015
Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper
Programmed cell death, or apoptosis, is a highly conserved cellular process that is crucial for tissue homeostasis under normal… (More)
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2013
2013
The 5′-3′ exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277–3p in Drosophila wing imaginal discs
Pacman/Xrn1 is a highly conserved exoribonuclease known to play a critical role in gene regulatory events such as control of mRNA… (More)
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2011
2011
RNA Granules Living a Post-transcriptional Life: the Trypanosomes' Case.
Trypanosomes are protozoan parasites responsible for recalcitrant infectious diseases such as Sleeping sickness and Chagas… (More)
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2008
2008
The 5'-3' exoribonuclease pacman is required for epithelial sheet sealing in Drosophila and genetically interacts with the phosphatase puckered.
BACKGROUND INFORMATION Ribonucleases have been well studied in yeast and bacteria, but their biological significance to… (More)
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2008
2008
The 5'-3' exoribonuclease Pacman is required for normal male fertility and is dynamically localized in cytoplasmic particles in Drosophila testis cells.
The exoribonuclease Xrn1 is widely recognised as a key component in the 5'-3' RNA degradation pathway. This enzyme is highly… (More)
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Highly Cited
2000
Highly Cited
2000
Cap-dependent deadenylation of mRNA.
Poly(A) tail removal is often the initial and rate-limiting step in mRNA decay and is also responsible for translational… (More)
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1980
1980
Purification and characterization of a poly(A)-specific exoribonuclease from calf thymus.
An exoribonuclease from calf thymus which specifically cleaves poly(A) in the single- or in the double-stranded form has been… (More)
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