negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation

Known as: cyclin catabolism, cyclin degradation, cyclin catabolic process 
The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and… (More)
National Institutes of Health

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2009
2009
The UBE3A/E6-AP is known to function both as an E3 ubiquitin ligase of the ubiquitin proteasome system and as a transcriptional… (More)
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Highly Cited
2007
Highly Cited
2007
Transformation and cancer growth are regulated by the coordinate actions of oncogenes and tumor suppressors. Here, we show that… (More)
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2004
2004
PURPOSE There is a need to identify cancer chemoprevention mechanisms. We reported previously that all-trans-retinoic acid (RA… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclin B1, the regulatory component of M phase-promoting factor (MPF), is degraded during the metaphase-anaphase transition in an… (More)
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Highly Cited
2001
Highly Cited
2001
In Saccharomyces cerevisiae, the phosphoprotein phosphatase Cdc14p plays a central role in exit from mitosis, by promoting B-type… (More)
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Highly Cited
1998
Highly Cited
1998
The activation of cyclin-dependent kinases (cdks) has been implicated in apoptosis induced by various stimuli. We find that the… (More)
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Highly Cited
1995
Highly Cited
1995
Cln3 cyclin of the budding yeast Saccharomyces cerevisiae is a key regulator of Start, a cell cycle event in G1 phase at which… (More)
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1992
1992
We have previously reported the identification of a hepatitis B virus (HBV) DNA integration in an intron of the cyclin A gene in… (More)
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Highly Cited
1991
Highly Cited
1991
A derivative of ubiquitin in which amino groups were blocked by reductive methylation was used to study the possible role of the… (More)
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Highly Cited
1990
Highly Cited
1990
THE cell cycles of early Xenopus embryos consist of a rapid succession of alternating S and M phases1. These cycles are… (More)
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