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negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

Known as: negative regulation of coenzyme F420-dependent nitroimidazole breakdown, down-regulation of coenzyme F420-dependent nitroimidazole breakdown, down-regulation of coenzyme F420-dependent nitroimidazole catabolism 
Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. [GOC… 
National Institutes of Health

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3 relations

Broader (1)

biological control
coenzyme F420-dependent bicyclic nitroimidazole catabolic processdown regulation of coenzyme F420-dependent nitroreductase activity

Papers overview

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2010
2010
NHC-catalysed annulation of enals to tethered dienones: efficient synthesis of bicyclic dienes.
Homoenolates generated from α,β-unsaturated aldehydes using NHC catalysis underwent facile addition to dibenzylidene… 
2007
2007
Trypanocidal nitroimidazole derivatives: relationships among chemical structure and genotoxic activity.
1996
1996
Synthesis and evaluation of a boronated nitroimidazole for boron neutron capture therapy.
We postulated that nitroimidazoles, previously used for radiosensitizing solid tumors, may be interesting templates as carriers… 
1996
1996
Uptake and retention of nitroimidazole-carboranes designed for boron neutron capture therapy in experimental murine tumours: detection by 11B magnetic resonance spectroscopy.
Two novel nitroimidazole-carboranes were examined for their uptake and retention in two experimental murine solid tumours and in… 
1994
1994
The synthesis and in vitro evaluation of a 99mtechnetium-nitroimidazole complex based on a bis(amine-phenol) ligand: comparison to BMS-181321.
We have developed a 99mTechnetium complex for imaging of hypoxic tissue (BMS-181321). Recently, another nitroimidazole derivative… 
1994
1994
Kinetics of a putative hypoxic tissue marker, technetium-99m-nitroimidazole (BMS181321), in normoxic, hypoxic, ischemic and stunned myocardium.
UNLABELLED This study focused on the kinetics of the newly developed 99mTc-nitroimidazole, propyleneamine oxime-1,2… 
1988
1988
Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
1987
1987
Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
1986
1986
The phosphate-group of DNA as a potential target for RSU-1069, a nitroimidazole-aziridine radiosensitizer.
Highly Cited
1976
Highly Cited
1976
Cytotoxicity of two nitroimidazole radiosensitizers in an in vitro tumor model.
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