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negative regulation of chondrocyte hypertrophy

Known as: down-regulation of chondrocyte hypertrophy, downregulation of chondrocyte hypertrophy, inhibition of chondrocyte hypertrophy 
Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
chondrocyte hypertrophy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily… 
Highly Cited
2016
Highly Cited
2016
MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2.
2016
2016
MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression
Chondrocyte hypertrophy, regulated by Runt-related transcription factor 2 (RUNX2) and matrix metalloproteinase 13 (MMP13), is a… 
Highly Cited
2009
Highly Cited
2009
The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation
Sequential proliferation, hypertrophy and maturation of chondrocytes are required for proper endochondral bone development and… 
2009
2009
Engineering of large cartilaginous tissues through the use of microchanneled hydrogels and rotational culture.
The development of functional engineered cartilaginous tissues of sufficient size that can be used clinically to treat large… 
2009
2009
Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification
The axial and appendicular skeleton of vertebrates develops by endochondral ossification, in which skeletogenic tissue is… 
Highly Cited
2008
Highly Cited
2008
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte… 
Highly Cited
2008
Highly Cited
2008
Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy
Objectives: To investigate changes in gene expression in fibrillated and intact human osteoarthritis (OA) cartilage for evidence… 
Highly Cited
2007
Highly Cited
2007
Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification
Chondrocyte hypertrophy during endochondral ossification is a well-controlled process in which proliferating chondrocytes stop… 
2007
2007
Tissue engineering of trachea-like cartilage grafts by using chondrocyte macroaggregate: experimental study in rabbits.
Treatment and management of tracheal defects remain challenges in head and neck surgery. The purposes of this study were to… 
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