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negative regulation of chondrocyte hypertrophy
Known as:
down-regulation of chondrocyte hypertrophy
, downregulation of chondrocyte hypertrophy
, inhibition of chondrocyte hypertrophy
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Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
biological control
chondrocyte hypertrophy
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
Yeri Alice Rim
,
Yoojun Nam
,
J. Ju
International Journal of Molecular Sciences
2020
Corpus ID: 214771892
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily…
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Highly Cited
2016
Highly Cited
2016
MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2.
Guoliang Zhang
,
Yanhong Sun
,
Yuewen Wang
,
Rui Liu
,
Yimin Bao
,
Qi Li
Cellular Immunology
2016
Corpus ID: 44904012
2016
2016
MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression
Weishen Chen
,
P. Sheng
,
+6 authors
Ziji Zhang
International Journal of Molecular Sciences
2016
Corpus ID: 16740154
Chondrocyte hypertrophy, regulated by Runt-related transcription factor 2 (RUNX2) and matrix metalloproteinase 13 (MMP13), is a…
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Highly Cited
2009
Highly Cited
2009
The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation
Xizhi Guo
,
K. K. Mak
,
M. Taketo
,
Yingzi Yang
PLoS ONE
2009
Corpus ID: 376450
Sequential proliferation, hypertrophy and maturation of chondrocytes are required for proper endochondral bone development and…
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2009
2009
Engineering of large cartilaginous tissues through the use of microchanneled hydrogels and rotational culture.
C. T. Buckley
,
S. Thorpe
,
D. Kelly
Tissue Engineering. Part A
2009
Corpus ID: 25464228
The development of functional engineered cartilaginous tissues of sufficient size that can be used clinically to treat large…
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2009
2009
Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification
Hui Zhu
,
A. Bendall
PLoS ONE
2009
Corpus ID: 2311979
The axial and appendicular skeleton of vertebrates develops by endochondral ossification, in which skeletogenic tissue is…
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Highly Cited
2008
Highly Cited
2008
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
K. K. Mak
,
H. Kronenberg
,
P. Chuang
,
S. Mackem
,
Yingzi Yang
Development
2008
Corpus ID: 2688488
Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte…
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Highly Cited
2008
Highly Cited
2008
Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy
C. Brew
,
P. Clegg
,
R. Boot-Handford
,
J. Andrew
,
T. Hardingham
Annals of the Rheumatic Diseases
2008
Corpus ID: 206863197
Objectives: To investigate changes in gene expression in fibrillated and intact human osteoarthritis (OA) cartilage for evidence…
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Highly Cited
2007
Highly Cited
2007
Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification
Kozo Morita
,
T. Miyamoto
,
+11 authors
T. Suda
Journal of Experimental Medicine
2007
Corpus ID: 11017267
Chondrocyte hypertrophy during endochondral ossification is a well-controlled process in which proliferating chondrocytes stop…
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2007
2007
Tissue engineering of trachea-like cartilage grafts by using chondrocyte macroaggregate: experimental study in rabbits.
Wei Wu
,
Xiaobing Cheng
,
Yi-min Zhao
,
Fulin Chen
,
Xing-hua Feng
,
T. Mao
Artificial Organs
2007
Corpus ID: 32614608
Treatment and management of tracheal defects remain challenges in head and neck surgery. The purposes of this study were to…
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