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negamycin

 
National Institutes of Health

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2014
2014
Negamycin (NEG) is a ribosome-targeting antibiotic that exhibits clinically promising activity. Its binding site and mode of… Expand
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Highly Cited
2008
Highly Cited
2008
The most common form of congenital muscular dystrophy is caused by a deficiency in the α2 chain of laminin‐211, a protein of the… Expand
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2007
2007
ABSTRACT Negamycin, a small-molecule inhibitor of protein synthesis, binds the Haloarcula marismortui 50S ribosomal subunit at a… Expand
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Highly Cited
2003
Highly Cited
2003
The ability of aminoglycoside antibiotics to promote read-through of nonsense mutations has attracted interest in these drugs as… Expand
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2003
2003
Negamycin 1 is a bactericidal antibiotic with activity against Gram-negative bacteria, and served as a template in an antibiotic… Expand
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1976
1976
The effect of negamycin and its derivatives on protein synthesis in an Escherichia coli cell-free system was determined. (1… Expand
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1976
1976
Various negamycin analogs were examined for (1) miscoding activity and (2) inhibition of the termination of protein synthesis… Expand
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1974
1974
Abstract In the presence of negamycin, the amount of ribosome-bound peptides during protein synthesis increased to 2 or 3 times… Expand
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Highly Cited
1971
Highly Cited
1971
 
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Highly Cited
1970
Highly Cited
1970
 
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