negamycin

 
National Institutes of Health

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2014
2014
Negamycin (NEG) is a ribosome-targeting antibiotic that exhibits clinically promising activity. Its binding site and mode of… (More)
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2014
2014
Negamycin is a natural product with broad-spectrum antibacterial activity and efficacy in animal models of infection. Although… (More)
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2012
2012
A series of (+)-negamycin 1 analogues were synthesized, and their readthrough-promoting activity was evaluated for nonsense… (More)
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2008
2008
BACKGROUND The most common form of congenital muscular dystrophy is caused by a deficiency in the alpha2 chain of laminin-211, a… (More)
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2007
2007
Negamycin, a small-molecule inhibitor of protein synthesis, binds the Haloarcula marismortui 50S ribosomal subunit at a single… (More)
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2003
2003
The ability of aminoglycoside antibiotics to promote read-through of nonsense mutations has attracted interest in these drugs as… (More)
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2003
2003
Negamycin 1 is a bactericidal antibiotic with activity against Gram-negative bacteria, and served as a template in an antibiotic… (More)
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2003
2003
The ability of aminoglycoside antibiotics to promote read-through of nonsense mutations has attracted interest in these drugs as… (More)
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1976
1976
Various negamycin analogs were examined for (1) miscoding activity and (2) inhibition of the termination of protein synthesis… (More)
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1976
1976
The effect of negamycin and its derivatives on protein synthesis in an Escherichia coli cell-free system was determined. (1… (More)
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