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negamycin

National Institutes of Health

Papers overview

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2014
2014
Significance The identification of negamycin’s binding site within helix 34 of the small subunit head domain and the elucidation… 
2011
2011
The APC tumor suppressor gene is frequently mutated in human colorectal cancer, with nonsense mutations accounting for 30% of all… 
Highly Cited
2008
Highly Cited
2008
The most common form of congenital muscular dystrophy is caused by a deficiency in the α2 chain of laminin‐211, a protein of the… 
2007
2007
ABSTRACT Negamycin, a small-molecule inhibitor of protein synthesis, binds the Haloarcula marismortui 50S ribosomal subunit at a… 
Highly Cited
2003
Highly Cited
2003
The ability of aminoglycoside antibiotics to promote read-through of nonsense mutations has attracted interest in these drugs as… 
1976
1976
Various negamycin analogs were examined for (1) miscoding activity and (2) inhibition of the termination of protein synthesis… 
1972
1972
Using various in vivo and in vitro systems, Mizuno et al.3>i} demonstrated that negamycin is a specific inhibitor of protein… 
Highly Cited
1972
Highly Cited
1972
Highly Cited
1971
Highly Cited
1971
Highly Cited
1970
Highly Cited
1970