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Whether the delta-opioid receptor (DOR) system can modulate behavioral effects of cocaine remains equivocal. We examined whether… Expand In the intestine, opioids produce antidiarrhoeal and constipating actions that are mediated by enteric neurones. Through… Expand Pharmacological studies performed in vivo suggested that the delta-opioid receptor could exist as two distinct subtypes, delta(1… Expand Although the interactions between the mu- and the delta-opiate receptor subtypes are well documented with regard to supraspinal… Expand The effects of the highly selective delta opioid receptor antagonists naltrindole (NTI) for delta 1 and delta 2 naltriben (NTB… Expand A number of recent investigations have proposed the existence of two pharmacologically distinct delta opioid receptor subtypes… Expand The possible involvement of delta 2 opioid receptors in the development of morphine dependence was investigated using selective… Expand The effects that naltriben (NTB) and naltrindole 5'-isothiocyanate (5'-NTII) have on acute morphine dependence were investigated… Expand The present study has investigated the direct opioid delta receptor-mediated antinociception produced by i.c.v. administration of… Expand Here we report on the design and synthesis of the first nonpeptide, nonequilibrium δ opioid receptor antagonist, naltrindole 5… Expand