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nafimidone alcohol

Known as: 1-(2-hydroxy-2-(2-naphthyl)ethyl)imidazole 
National Institutes of Health

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2 relations

Broader (1)

Naphazoline
analogs & derivatives

Papers overview

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Highly Cited
2010
Highly Cited
2010
Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives.
1990
1990
The metabolism of nafimidone hydrochloride in the dog, primates and man.
1. The biotransformation of nafimidone, an imidazole-substituted anticonvulsant, has been studied by characterization of urinary… 
1987
1987
Disposition of nafimidone in rats.
The absorption, distribution, excretion, and metabolism of 14C-nafimidone, a novel anticonvulsant, have been studied in rats… 
1987
1987
Inhibition and induction of hepatic drug metabolism in rats and mice by nafimidone and its major metabolite nafimidone alcohol.
Nafimidone, a candidate anticonvulsant agent, and its metabolite (nafimidone alcohol) demonstrated potent inhibition of hepatic… 
1987
1987
Pharmacokinetics of Nafimidone in Patients with Chronic Intractable Epilepsy
SummaryNafimidone is a new antiepileptic drug which may be effective in partial onset seizures. We studied the pharmacokinetics… 
1987
1987
High-performance liquid chromatographic determination of nafimidone and its major metabolite nafimidone alcohol in human plasma and urine.
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