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myosin light chain kinase activity

Known as: myosin kinase activity, MLCkase activity, myosin light-chain kinase 
Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate. [EC:2.7.11.18]
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
TNF-alpha plays a central role in the intestinal inflammation of various inflammatory disorders including Crohn's disease (CD… Expand
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Review
2003
Review
2003
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II reflects the ratio of activities of myosin light-chain kinase (MLCK) to… Expand
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Highly Cited
2003
Highly Cited
2003
To identify airway pathologic abnormalities selectively associated with severe asthma, we examined 10 control subjects, 10… Expand
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Highly Cited
1999
Highly Cited
1999
Contraction and relaxation of smooth muscle are regulated by myosin light-chain kinase and myosin phosphatase through… Expand
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Highly Cited
1997
Highly Cited
1997
Abnormal smooth-muscle contractility may be a major cause of disease states such as hypertension, and a smooth-muscle relaxant… Expand
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Highly Cited
1997
Highly Cited
1997
Cyclin-dependent kinases (cdk) play an essential role in the intracellular control of the cell division cycle (cdc). These… Expand
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Highly Cited
1997
Highly Cited
1997
Tight junctions serve as the rate-limiting barrier to passive movement of hydrophilic solutes across intestinal epithelia. After… Expand
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Review
1994
Review
1994
Smooth muscle cells in the walls of many organs are vital for most bodily functions, and their abnormalities contribute to a… Expand
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Review
1994
Review
1994
  • H. Lum, A. Malik
  • The American journal of physiology
  • 1994
  • Corpus ID: 25687932
The increase in endothelial permeability in response to inflammatory mediators such as alpha-thrombin and histamine is… Expand
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Highly Cited
1989
Highly Cited
1989
PHOSPHORYLATION of myosin light chains by a calmodulin-myosin light-chain kinase (MLCK) pathway is considered to be responsible… Expand
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