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myo-inositol-1 (or 4)-monophosphatase

Known as: inositol-1-phosphate phosphohydrolase, myo-inositol monophosphatase, myo-inositol-1-phosphatase 
 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Lithium is the most effective mood stabilizer for the treatment of bipolar disorder, but it is toxic at only twice the… Expand
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Highly Cited
2010
Highly Cited
2010
Staphylococcus aureus is a potent biofilm former on host tissue and medical implants, and biofilm growth is a critical virulence… Expand
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Highly Cited
2008
Highly Cited
2008
Huntington's disease (HD) is caused by a polyglutamine expansion mutation in the huntingtin protein that confers a toxic gain-of… Expand
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Highly Cited
2003
Highly Cited
2003
Glycogen synthase kinase-3 (GSK-3) is a critical, negative regulator of diverse signaling pathways. Lithium is a direct inhibitor… Expand
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Highly Cited
2001
Highly Cited
2001
1 One popular model for the activation of store‐operated Ca2+ influx is the secretion‐like coupling mechanism, in which… Expand
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Highly Cited
1996
Highly Cited
1996
  • P. Klein, D. Melton
  • Proceedings of the National Academy of Sciences…
  • 1996
  • Corpus ID: 9773142
Lithium, one of the most effective drugs for the treatment of bipolar (manic-depressive) disorder, also has dramatic effects on… Expand
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Highly Cited
1995
Highly Cited
1995
myo-Inositol monophosphatase (IMP) is a soluble, Li(+)-sensitive protein that catalyzes the removal of a phosphate from myo… Expand
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Review
1991
Review
1991
The ability of lithium to exert profound and selective psychopharmacological effects to ameliorate manic-depressive psychosis has… Expand
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Review
1990
Review
1990
Studies of phosphatidylinositol signaling pathways are entering a new phase in which molecular genetic techniques are providing… Expand
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Highly Cited
1988
Highly Cited
1988
1. An inositol monophosphatase was purified to homogeneity from bovine brain. 2. The enzyme is a dimer of subunit Mr 29,000. 3… Expand
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