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mycophenolic acid glucuronide

Known as: MPAG cpd 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

GlucuronidesMycophenolic Acid
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end‐stage renal disease and transplant patients: a pilot study
Abstract:  Background:  Promising data regarding the safety and efficacy of gastric bypass surgery (GBS) as an option to address… 
Highly Cited
2005
Highly Cited
2005
Enteric‐coated mycophenolate sodium delivers bioequivalent MPA exposure compared with mycophenolate mofetil
Abstract:  Mycophenolic acid (MPA), the active moiety of mycophenolate mofetil (MMF), is routinely used as an adjunct… 
Highly Cited
2004
Highly Cited
2004
Cyclosporin A, but Not Tacrolimus, Inhibits the Biliary Excretion of Mycophenolic Acid Glucuronide Possibly Mediated by Multidrug Resistance-Associated Protein 2 in Rats
The onset of diarrhea after the administration of mycophenolate mofetil (MMF) is possibly associated with the biliary excretion… 
Highly Cited
2002
Highly Cited
2002
Pharmacokinetics and Protein Adduct Formation of the Pharmacologically Active Acyl Glucuronide Metabolite of Mycophenolic Acid in Pediatric Renal Transplant Recipients
The acyl glucuronide metabolite (AcMPAG) of mycophenolic acid (MPA) has been found to possess both immunosuppressive and pro… 
Highly Cited
2002
Highly Cited
2002
Mycophenolic Acid and Mycophenolic Acid Glucuronide Pharmacokinetics in Pediatric Liver Transplant Recipients: Effect of Cyclosporine and Tacrolimus Comedication
Determinants of the wide interindividual variability of the pharmacokinetics of mycophenolic acid (MPA) in 21 stable pediatric… 
Highly Cited
2001
Highly Cited
2001
Comparison of the Effects of Tacrolimus and Cyclosporine on the Pharmacokinetics of Mycophenolic Acid
Mycophenolate mofetil (MMF) is almost completely absorbed from the gut and is rapidly de-esterified into its active drug… 
Highly Cited
2001
Highly Cited
2001
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes.
AIMS To estimate the relative contribution of liver, kidney and jejunum to MPA elimination via glucuronidation from in vitro… 
Highly Cited
2001
Highly Cited
2001
Pharmacokinetics of Mycophenolic Acid after Mycophenolate Mofetil Administration in Liver Transplant Patients Treated with Tacrolimus
The pharmacokinetics of mycophenolic acid (MPA) was studied after oral administration of mycophenolate mofetil (MMF) in 8 liver… 
Highly Cited
1996
Highly Cited
1996
Pharmacokinetics and Bioavailability of Mycophenolate Mofetil in Healthy Subjects after Single‐Dose Oral and Intravenous Administration
A randomized, crossover study of 12 healthy volunteers was conducted with single, 1.5‐g doses of mycophenolate mofetil (MMF), a… 
Review
1995
Review
1995
Mycophenolic Acid: Measurement and Relationship to Pharmacologie Effects
Summary Validated high-performance liquid chromatographic (HPLC) methods have been developed for the reliable measurement in… 
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