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muramyl tripeptide phosphatidylethanolamine

Known as: muramylNAc-Ala-isoGln-Lys-tripeptide-PE, Mifamurtide, muramyl tripeptide-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine conjugate 
A liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. Muramyl… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
For the past 30 years, improvements in the survival of patients with osteosarcoma have been mostly incremental. Despite evidence… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The addition of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) to chemotherapy has been shown to… Expand
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Review
2009
Review
2009
  • Paul A. Meyers
  • Expert review of anticancer therapy
  • 2009
  • Corpus ID: 29512704
Osteosarcoma is an ultraorphan disease. There are approximately 1000 new patients diagnosed with osteosarcoma each year in the… Expand
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Highly Cited
2007
Highly Cited
2007
Nucleotide-binding oligomerization domain (Nod)2 is a sensor of muramyl dipeptides (MDP) derived from bacterial peptidoglycan… Expand
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Review
2006
Review
2006
About one third of osteosarcoma patients develop lung metastasis refractory to chemotherapy. Recent studies indicate that… Expand
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Highly Cited
1996
Highly Cited
1996
Interleukin 12 (IL-12) strongly augments gamma interferon production by natural killer (NK) and T cells. IL-12 also promotes… Expand
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Highly Cited
1995
Highly Cited
1995
Two randomized, double-blind clinical trials in dogs with spontaneous appendicular osteosarcoma treated with combination… Expand
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Highly Cited
1995
Highly Cited
1995
Canine splenic hemangiosarcoma (HSA) is a spontaneous tumor with high metastatic potential. Despite surgical excision, most dogs… Expand
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Highly Cited
1994
Highly Cited
1994
Antibodies to Pfs25, a cysteine-rich 25-kDa protein present on the surface of Plasmodium falciparum zygotes, can completely block… Expand
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Highly Cited
1992
Highly Cited
1992
PURPOSE A phase II trial that uses liposome-encapsulated muramyl tripeptide phosphatidylethanolamine (L-MTP-PE) in patients with… Expand
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