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moxifloxacin

Known as: 1-cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid, MOXI 
A fluoroquinolone antibiotic with antibacterial activity. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and… 
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Importance In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of… 
Highly Cited
2014
Highly Cited
2014
BACKGROUND Early-phase and preclinical studies suggest that moxifloxacin-containing regimens could allow for effective 4-month… 
Highly Cited
2014
Highly Cited
2014
BACKGROUND Tuberculosis regimens that are shorter and simpler than the current 6-month daily regimen are needed. METHODS We… 
Highly Cited
2011
Highly Cited
2011
Here, we compile the Biopharmaceutics Drug Disposition Classification System (BDDCS) classification for 927 drugs, which include… 
Highly Cited
2009
Highly Cited
2009
RATIONALE Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and in a mouse model of antituberculosis… 
Review
2007
Review
2007
  • H. Wexler
  • Clinical Microbiology Reviews
  • 2007
  • Corpus ID: 30170463
SUMMARY Summary: Bacteroides species are significant clinical pathogens and are found in most anaerobic infections, with an… 
Highly Cited
2006
Highly Cited
2006
Nuclear factor kappa B (NF-κB) transcription factors regulate several important physiological processes, including inflammation… 
Highly Cited
2005
Highly Cited
2005
BACKGROUND Recent reports suggest that the rate and severity of Clostridium difficile-associated disease in the United States are… 
Highly Cited
2004
Highly Cited
2004
Tuberculosis continues to be a major cause of morbidity and mortality in the world. The expansion of tuberculosis control… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Moxifloxacin is a quinolone antimicrobial that has potent activity against Mycobacterium tuberculosis. To optimize…