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moxifloxacin

Known as: 1-cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid, MOXI 
A fluoroquinolone antibiotic with antibacterial activity. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and… 
National Institutes of Health

Related topics

Related topics

39 relations
AmiodaroneAmiodarone hydrochlorideAvelox 400 mg oral tablet includes Avelox ABC PackBacterial Infections

Broader (3)

Anti-Bacterial AgentsFluoroquinolonesTopoisomerase II Inhibitors

Narrower (5)

AveloxMoxifloxacin hydrochlorideOctegraProflox

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Prevalence of Primary Fluoroquinolone Resistance Among Clinical Isolates of Helicobacter pylori at a University Hospital in Southern Taiwan
Background:  Fluoroquinolone‐containing therapy is effective in eradicating Helicobacter pylori. However, the resistance rate of… 
2009
2009
Simultaneous determination of bisoprolol and hydrochlorothiazide in human plasma by HPLC coupled with tandem mass spectrometry.
Highly Cited
2008
Highly Cited
2008
Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study--a randomized clinical trial.
BACKGROUND The aim of this study was to show that sequential intravenous and oral moxifloxacin monotherapy (400 mg once per day… 
Highly Cited
2007
Highly Cited
2007
Fourth-generation fluoroquinolone-resistant bacterial keratitis.
Highly Cited
2006
Highly Cited
2006
Fourth-generation fluoroquinolone penetration into the aqueous humor in humans.
Highly Cited
2006
Highly Cited
2006
Cardiovascular monkey telemetry: sensitivity to detect QT interval prolongation.
Highly Cited
2005
Highly Cited
2005
Clinical Assessment of Drug‐induced QT Prolongation in Association with Heart Rate Changes
Highly Cited
2004
Highly Cited
2004
Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults.
STUDY OBJECTIVE To determine the steady-state, extracellular, and intracellular pulmonary disposition of moxifloxacin (MXF… 
Highly Cited
2004
Highly Cited
2004
Evaluation of vardenafil and sildenafil on cardiac repolarization.
2000
2000
Comparison of an in vitro cellular phototoxicity model against controlled clinical trials of fluoroquinolone skin phototoxicity.
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