motavizumab

Known as: Immunoglobulin G1, anti-(respiratory syncytial virus glocoprotein F) (human-mouse monoclonal MEDI-524 gamma-1-chain), disulfide with human-mouse monoclonal MEDI-524 kappa-chain, dimer 
A humanized monoclonal antibody directed against the respiratory syncytial virus (RSV) fusion glycoprotein (F-protein), with activity against RSV… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
BACKGROUND This study was conducted to determine whether treatment with motavizumab, an anti-respiratory syncytial virus (RSV… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
The study objective was to evaluate the pharmacokinetics (PK), antidrug antibody (ADA), and safety of motavizumab-YTE… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Respiratory syncytial virus (RSV) invades host cells via a type I fusion (F) glycoprotein that undergoes dramatic structural… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2011
2011
Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in infants, but an effective vaccine has not… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2011
2011
BACKGROUND Palivizumab is a US Food and Drug Administration-approved monoclonal antibody for the prevention of respiratory… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
OBJECTIVE Palivizumab reduces respiratory syncytial virus (RSV) hospitalization in children at high risk by approximately 50… (More)
Is this relevant?
2010
2010
Motavizumab is ∼tenfold more potent than its predecessor, palivizumab (Synagis), the FDA-approved monoclonal antibody used to… (More)
  • figure 1
  • figure 2
Is this relevant?
2010
2010
Respiratory syncytial virus (RSV) is a major cause of virus-induced respiratory disease and hospitalization in infants… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2008
Review
2008
Antibodies mediate humoral immune responses and play key roles in the defense of viral infection by the recognition… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Respiratory syncytial virus (RSV) is the leading cause of viral bronchiolitis and pneumonia in infants and children. Currently… (More)
Is this relevant?