morphogen activity

Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient. [GOC:go_curators]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
024620002017

Papers overview

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2014
2014
The conserved family of Hedgehog (Hh) proteins acts as short- and long-range secreted morphogens, controlling tissue patterning… (More)
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2013
2013
The Drosophila wing imaginal disc is a key model organ for molecular developmental genetics. Wing disc studies are generally… (More)
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2011
2011
Developmental patterning relies on morphogen concentration gradients, which generally provide invariable positional information… (More)
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2011
2011
Orchestration of spatial organization by signaling gradients--morphogen gradients--is a fundamental principle in animal… (More)
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Highly Cited
2010
Highly Cited
2010
In many instances during development, morphogens specify cell fates by forming concentration gradients. In the Drosophila… (More)
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2009
2009
The proper development of tissues requires morphogen activity that dictates the appropriate growth and differentiation of each… (More)
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Highly Cited
2004
Highly Cited
2004
The signaling molecules Hedgehog (Hh), Decapentaplegic (Dpp) and Wingless (Wg) function as morphogens and organize wing… (More)
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Highly Cited
2004
Highly Cited
2004
The glypican family of heparan sulfate proteoglycans has been implicated in formation of morphogen gradients. Here, we examine… (More)
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Highly Cited
2001
Highly Cited
2001
Cell pattern in the ventral neural tube is organized by Sonic hedgehog (Shh) secreted by floor plate cells. To assay the range of… (More)
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2000
2000
Morphogens are secreted proteins that organize surrounding tissues into distinct territories and are thought to act as a function… (More)
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