morphine-3-glucuronide

 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Glucuronidation is a major detoxification pathway for endogenous and exogenous compounds in mammals that results in the… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The efflux transporter P-glycoprotein, a member of the adenosine triphosphate-binding cassette superfamily, is a major… (More)
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2001
2001
In humans, hydromorphone (HMOR) is metabolised principally by conjugation with glucuronic acid to form hydromorphone-3… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Animal and human studies indicate the existence of important sex-related differences in opioid-mediated behavior. In… (More)
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Highly Cited
1997
Highly Cited
1997
A human UDP-glucuronosyltransferase (UGT) catalyzing the glucuronidation of morphine has been identified. A full length cDNA was… (More)
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Review
1997
Review
1997
Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long-term treatment of severe pain… (More)
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1994
1994
To assess whether stoichiometric manipulation of morphine (M) metabolism can enhance analgesia or slow the development of M… (More)
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Review
1991
Review
1991
Morphine (M) is recommended by the World Health Organization as the treatment of choice for moderate-to-severe cancer pain… (More)
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Highly Cited
1990
Highly Cited
1990
The pharmacokinetic parameters of morphine, morphine-6-glucuronide, and morphine-3-glucuronide were studied after single-dose… (More)
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