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monoclonal antibody huJ591
Known as:
MOAB huJ591
, huJ591
A humanized monoclonal antibody (MoAb) against the external domain of the Prostate-specific membrane antigen (PSMA), overexpressed in the malignant…
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National Institutes of Health
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Related topics
Related topics
1 relation
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Cerenkov Luminescence Imaging as a Modality to Evaluate Antibody-Based PET Radiotracers
Jimson W D'souza
,
H. Hensley
,
+5 authors
M. Robinson
Journal of Nuclear Medicine
2017
Corpus ID: 10267192
Antibodies, and engineered antibody fragments, labeled with radioisotopes are being developed as radiotracers for the detection…
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2016
2016
A phase I/IIa trial of prostate specific membrane antigen (PSMA) positron emission tomography (PET) imaging with 89Zr-Df-IAB2M in metastatic prostate cancer (PCa).
M. Morris
,
Danny F. Martinez
,
+15 authors
N. Pandit-Taskar
2016
Corpus ID: 78860423
287 Background: There is a pressing need for improved imaging biomarkers to identify disease distribution and response in both…
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Highly Cited
2015
Highly Cited
2015
A Phase I/II Study for Analytic Validation of 89Zr-J591 ImmunoPET as a Molecular Imaging Agent for Metastatic Prostate Cancer
N. Pandit-Taskar
,
J. O’Donoghue
,
+22 authors
M. Morris
Clinical Cancer Research
2015
Corpus ID: 11699042
Purpose: Standard imaging for assessing osseous metastases in advanced prostate cancer remains focused on altered bone metabolism…
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Highly Cited
2014
Highly Cited
2014
89Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer
N. Pandit-Taskar
,
J. O’Donoghue
,
+19 authors
S. Larson
European Journal of Nuclear Medicine and…
2014
Corpus ID: 26971842
PurposeGiven the bone tropism of prostate cancer, conventional imaging modalities poorly identify or quantify metastatic disease…
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Highly Cited
2014
Highly Cited
2014
Noninvasive Imaging of PSMA in Prostate Tumors with 89Zr-Labeled huJ591 Engineered Antibody Fragments: The Faster Alternatives
Nerissa T. Viola-Villegas
,
Kuntal K. Sevak
,
+5 authors
Jason S. Lewis
Molecular Pharmaceutics
2014
Corpus ID: 30978748
Engineered antibody fragments offer faster delivery with retained tumor specificity and rapid clearance from nontumor tissues…
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Review
2013
Review
2013
Prostate-specific membrane antigen-based imaging.
J. Osborne
,
N. Akhtar
,
S. Vallabhajosula
,
Alok Anand
,
K. Deh
,
S. Tagawa
Urologic oncology
2013
Corpus ID: 23097675
Review
2009
Review
2009
New targeted probes for radioimaging of angiogenesis.
T. H. Stollman
,
T. Ruers
,
W. Oyen
,
O. Boerman
Methods
2009
Corpus ID: 27956956
2005
2005
Mass spectral analyses of labile DOTA-NHS and heterogeneity determination of DOTA or DM1 conjugated anti-PSMA antibody for prostate cancer therapy.
S. Lu
,
E. Takach
,
M. Solomon
,
Qing Zhu
,
S. Law
,
F. Hsieh
Journal of Pharmacy and Science
2005
Corpus ID: 257986
Prostate specific membrane antigen (PSMA) is a well-characterized glycoprotein overexpressed on the surface of prostate cancer…
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Highly Cited
2004
Highly Cited
2004
Radioimmunotherapy of prostate cancer in human xenografts using monoclonal antibodies specific to prostate specific membrane antigen (PSMA): Studies in nude mice
S. Vallabhajosula
,
P. Smith-Jones
,
V. Navarro
,
S. Goldsmith
,
N. Bander
The Prostate
2004
Corpus ID: 40673824
Prostate specific membrane antigen (PSMA), expressed by virtually all prostate cancers is an ideal target for targeted therapy of…
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Review
2003
Review
2003
Clinical use of monoclonal antibody HuJ591 therapy: targeting prostate specific membrane antigen.
D. Nanus
,
M. Milowsky
,
+4 authors
N. Bander
Journal of Urology
2003
Corpus ID: 7544815
PURPOSE Prostate specific membrane antigen (PSMA) is a cell surface peptidase highly expressed by malignant prostate epithelial…
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