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monoclonal antibody huJ591

Known as: MOAB huJ591, huJ591 
A humanized monoclonal antibody (MoAb) against the external domain of the Prostate-specific membrane antigen (PSMA), overexpressed in the malignant… Expand
National Institutes of Health

Papers overview

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2017
2017
Antibodies, and engineered antibody fragments, labeled with radioisotopes are being developed as radiotracers for the detection… Expand
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2016
2016
287 Background: There is a pressing need for improved imaging biomarkers to identify disease distribution and response in both… Expand
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Highly Cited
2015
Highly Cited
2015
Purpose: Standard imaging for assessing osseous metastases in advanced prostate cancer remains focused on altered bone metabolism… Expand
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2015
2015
Neeta Pandit-Taskar, Joseph A. O’Donoghue, Jeremy C. Durack, Serge Lyashchenko, Sarah M. Cheal, Volkan Beylergil, Robert A… Expand
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Highly Cited
2014
Highly Cited
2014
PurposeGiven the bone tropism of prostate cancer, conventional imaging modalities poorly identify or quantify metastatic disease… Expand
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Highly Cited
2014
Highly Cited
2014
Engineered antibody fragments offer faster delivery with retained tumor specificity and rapid clearance from nontumor tissues… Expand
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Review
2013
Review
2013
Prostate cancer (CaP) is the most common noncutaneous malignancy affecting men in North America. Despite significant efforts… Expand
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2005
2005
Prostate specific membrane antigen (PSMA) is a well-characterized glycoprotein overexpressed on the surface of prostate cancer… Expand
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Highly Cited
2004
Highly Cited
2004
Prostate specific membrane antigen (PSMA), expressed by virtually all prostate cancers is an ideal target for targeted therapy of… Expand
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Review
2003
Review
2003
PURPOSE Prostate specific membrane antigen (PSMA) is a cell surface peptidase highly expressed by malignant prostate epithelial… Expand
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