FAQ

monoclonal antibody LL2

Known as: LL2, LL2 monoclonal antibody, MoAb LL2 
A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2017
051019652017

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4 relations
Monoclonal Antibodiesantigen bindingepratuzumabtechnetium Tc 99m monoclonal antibody LL2

Related mentions per year

Related mentions per year

1948-2018
19401960198020002020
monoclonal antibody LL2
Monoclonal Antibodies
antigen binding
epratuzumab
technetium Tc 99m monoclonal antibody LL2

Papers overview

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2003
2003
Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb/IIIa antagonist XV454.
Platelets are known to play a role in blood borne metastasis. Previous experimental studies have suggested that platelet GpIIb… (More)
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1999
1999
Pharmacokinetics, dosimetry, and initial therapeutic results with 131I- and (111)In-/90Y-labeled humanized LL2 anti-CD22 monoclonal antibody in patients with relapsed, refractory non-Hodgkin's…
The pharmacokinetics, dosimetry, and immunogenicity of 131I- and (111)In-/90Y-humanized LL2 (hLL2) anti-CD22 monoclonal… (More)
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1999
1999
Radioimmunotherapy using 131I-labeled anti-CD22 monoclonal antibody (LL2) in patients with previously treated B-cell lymphomas.
Experience in using rapidly internalizing antibodies, such as the anti-CD22 antibody, for radioimmunotherapy of B-cell lymphomas… (More)
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1999
1999
Labeling of monoclonal antibodies with diethylenetriaminepentaacetic acid-appended radioiodinated peptides containing D-amino acids.
The optimal use of radioiodinated internalizing monoclonal antibodies (mAbs) for radioimmunotherapy necessitates the development… (More)
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1995
1995
Treatment of non-Hodgkin's lymphoma with radiolabeled murine, chimeric, or humanized LL2, an anti-CD22 monoclonal antibody.
LL2 is a murine IgG2a anti-CD22 monoclonal antibody found to react with virtually all non-Hodgkin's lymphomas (NHLs). Twenty-one… (More)
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1995
1995
Construction and characterization of a humanized, internalizing, B-cell (CD22)-specific, leukemia/lymphoma antibody, LL2.
The murine monoclonal antibody, LL2, is a B-cell (CD22)-specific IgG2a which has been demonstrated to be clinically significant… (More)
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1994
1994
Internalization and intracellular processing of an anti-B-cell lymphoma monoclonal antibody, LL2.
The successful clinical experience with antibody LL2 (an IgG2a, anti-B-cell lymphoma antibody) in radioimmunodetection and… (More)
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1993
1993
Epitope specificity of the anti-(B cell lymphoma) monoclonal antibody, LL2
LL2 is a murine monoclonal antibody IgG2a reactive with B cells and non-Hodgkin's B-cell lymphoma, which, in a radioiodinated… (More)
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1993
1993
Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice.
We have produced immunotoxins using LL2, a monoclonal antibody which binds to human B-cell lymphomas and which, in a… (More)
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Highly Cited
1991
Highly Cited
1991
Targeting, dosimetry, and radioimmunotherapy of B-cell lymphomas with iodine-131-labeled LL2 monoclonal antibody.
Sixteen patients with non-Hodgkin's lymphoma were infused with 6.2 to 58.2 mCi (0.2 to 3.9 mg) doses of radioactive iodine (131I… (More)
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