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monoclonal antibody CC49

Known as: CC-49 Monoclonal Antibody, Monoclonal Antibody CC-49, MOAB CC49 
A second-generation murine monoclonal antibody based on the antibody B72.3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72… Expand
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
UNLABELLED For calculation of radiation dose to the marrow, standard dosimetry for radiopharmaceuticals that do not bind to the… Expand
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Highly Cited
1999
Highly Cited
1999
Cancer therapies using genes and other macromolecules might realize their full clinical potential if they could be delivered to… Expand
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Highly Cited
1999
Highly Cited
1999
UNLABELLED Monoclonal antibodies (MAbs) have been proven useful in clinical studies for both diagnostic and therapeutic… Expand
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1999
1999
A novel strategy was developed in which an antibody scFv fragment of the monoclonal antibody (MAb) CC49 was modified by… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Twenty-seven ovarian cancer patients who failed chemotherapy entered a phase I/II trial of intraperitoneal 177Lu-CC49… Expand
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Highly Cited
1995
Highly Cited
1995
CC49, a murine monoclonal antibody that recognizes the tumor-associated glycoprotein 72, was conjugated to the chemical chelate 1… Expand
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Highly Cited
1994
Highly Cited
1994
Background. Patients with transmurally invasive, lymph node negative colorectal carcinoma (Dukes' B) have a 5‐year survival rate… Expand
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Highly Cited
1993
Highly Cited
1993
The effects of linker length on binding affinity and degree of aggregation have been examined in the antifluorescein 4-4-20 and… Expand
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Highly Cited
1992
Highly Cited
1992
Single-chain antigen-binding proteins, or sFvs, represent potentially unique molecules for targeted delivery of drugs, toxins, or… Expand
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Highly Cited
1991
Highly Cited
1991
CC49 is a "second generation" monoclonal antibody to B72.3, which reacts with the pancarcinoma antigen TAG-72. CC49 has been… Expand
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