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monoclonal antibody 806

Known as: mAb 806, mAb-806, DEPATUXIZUMAB 
A humanized monoclonal antibody (MoAb) against human epidermal growth factor receptor (EGFR) with antineoplastic activity. Depatuxizumab targets the… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Glioblastoma is an intrinsic brain tumour thought to arise from neuroglial progenitor cells. Its incidence increases steadily… Expand
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2019
2019
Abstract Background Patients with glioblastoma (GBM) have a dismal prognosis. Nearly all will relapse with no clear standard of… Expand
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2017
2017
PurposePatients with recurrent glioblastoma (rGBM) have a poor prognosis. Epidermal growth factor receptor (EGFR) gene… Expand
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2016
2016
Exosomes are small, 40–130 nm secreted extracellular vesicles that recently have become the subject of intense focus as agents of… Expand
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Review
2012
Review
2012
Epidermal growth factor receptor (EGFR) and its most common extracellular mutant, EGFRvIII, are important therapeutic targets in… Expand
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Highly Cited
2007
Highly Cited
2007
Overexpression of the epidermal growth factor receptor (EGFR) in epithelial tumors is associated with poor prognosis and is the… Expand
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2006
2006
In this work, we combined computational protein-protein docking with computational and experimental mutagenesis to predict the… Expand
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2005
2005
Overexpression of the EGFR is commonly caused by EGFR gene amplification and is sometimes associated with expression of a variant… Expand
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Highly Cited
2004
Highly Cited
2004
The epidermal growth factor receptor (EGFR) is overexpressed in many epithelial cancers, an observation often correlated with… Expand
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