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monoclonal antibody 4B5 anti-idiotype vaccine

Known as: 4B5 monoclonal antibody anti-idiotype vaccine, MOAB 4B5, MoAb 4B5 anti-idiotype vaccine 
A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and… 
National Institutes of Health

Papers overview

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2016
2016
Targeting lymphoma with precision using semisynthetic anti-idiotype peptibodies
Significance Idiotype is a true tumor-specific surface marker on lymphoma cells, and cross-linking idiotype can directly trigger… 
1995
1995
Assessment of a functional role of auto‐anti‐idiotypes in idiotype dominance
We have used a well‐defined idiotypic system, the cross‐reactive idiotype of A strain (CRIA) (Ab1) idiotype generated in A/J mice… 
1990
1990
A major crossreactive idiotype associated with human antibodies to the Haemophilus influenzae b polysaccharide. Expression in relation to age and immunoglobulin G subclass.
Using idiotypic analysis, we examined the variable (V) region diversity of human antibodies specific for the capsular… 
1988
1988
Studies of a common idiotype PR4 in autoimmune rheumatic disease.
A new common idiotype, designated PR4, is described. This idiotype was originally identified on a human hybridoma-derived… 
1985
1985
Thymus‐independent induction of idiotype suppression in newborn mice by syngeneic anti‐idiotype antisera
BALB/c and BALB/c nu/nu mice were shown to express to a variable extent in their response against dextran B1355S (Dex), an… 
1984
1984
Idiotypic analysis of potential and available repertoires in the arsonate system
We have shown that, by suitable idiotypic manipulation, BALB/c mice can express the major cross-reactive idiotype (CRI) of A/J… 
1983
1983
Idiotype connectance in the immune system. I. Expression of a cross- reactive idiotype on induced anti-p-azophenylarsonate antibodies and on endogenous antibodies not specific for arsonate
A new cross-reactive idiotope family (CRIAD8) is described that contains subpopulations of antibodies binding to different… 
1982
1982
Lack of inter-animal cross-reaction of anti-acetylcholine receptor antibodies at the receptor-binding site as demonstrated by heterologous anti-idiotype antisera: implications for immunotherapy of…
Anti-idiotype antisera were raised in rabbits by immunization with purified sheep anti-Torpedo receptor antibodies. The antisera… 
1980
1980
Idiotype-specific tolerance: preferential alteration of idiotype expression after neonatal exposure to tolerogen.
The development of HOPC-8 idiotype-positive and HOPC-8 idiotype-negative B cell subpopulations involved in the immune response to… 
1979
1979
Genetic control of the immune response to the terpolymer L‐glutamic acid60‐L‐aIanine30‐L‐tyrosme10 (GAT): II. Characterization of a cross‐reactive idiotype associated with anti‐GAT antibodies from…
An anti‐idiotypic antiserum specific for the antibodies directed against the terpolymer poly(Glu60, Ala30, Tyr10), referred to as… 
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