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monoclonal antibody 4B5 anti-idiotype vaccine

Known as: 4B5 monoclonal antibody anti-idiotype vaccine, MOAB 4B5, MoAb 4B5 anti-idiotype vaccine 
A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and… Expand
National Institutes of Health

Papers overview

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2017
2017
A Possible Role for Idiotype/Anti-idiotype B–T Cell Interactions in Maintaining Immune Memory
Variable regions of both B-cell receptors (BCRs) and T-cell receptors (TCRs) are completely formed in the postnatal period, and… Expand
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2016
2016
Targeting lymphoma with precision using semisynthetic anti-idiotype peptibodies
Significance Idiotype is a true tumor-specific surface marker on lymphoma cells, and cross-linking idiotype can directly trigger… Expand
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2005
2005
Induction of delayed-type hypersensitivity responses by monoclonal anti-idiotypic antibodies to tumor cells expressing carcinoembryonic antigen and tumor-associated glycoprotein-72
The use of anti-idiotypic antibodies as immunogens represents one potential approach to active specific immunotherapy of cancer… Expand
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2003
2003
[Immuno-therapeutic study of anti-idiotype minibody (single chain Fv-CH3) on ovarian carcinoma bearing mice].
OBJECTIVE An anti-idiotypic minibody with optimal antigenicity which mimicking ovarian cancer antigen was used for therapeutic… Expand
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1995
1995
Assessment of a functional role of auto-anti-idiotypes in idiotype dominance.
We have used a well-defined idiotypic system, the cross-reactive idiotype of A strain (CRIA) (Ab1) idiotype generated in A/J mice… Expand
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1991
1991
The major rheumatoid factor crossreactive idiotype and IgA rheumatoid factor in juvenile rheumatoid arthritis.
One third of patients with juvenile rheumatoid arthritis (JRA) are seronegative for classic or hidden IgM rheumatoid factor (RF… Expand
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1990
1990
A major crossreactive idiotype associated with human antibodies to the Haemophilus influenzae b polysaccharide. Expression in relation to age and immunoglobulin G subclass.
Using idiotypic analysis, we examined the variable (V) region diversity of human antibodies specific for the capsular… Expand
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1988
1988
Studies of a common idiotype PR4 in autoimmune rheumatic disease.
A new common idiotype, designated PR4, is described. This idiotype was originally identified on a human hybridoma-derived… Expand
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1983
1983
Idiotype connectance in the immune system. I. Expression of a cross- reactive idiotype on induced anti-p-azophenylarsonate antibodies and on endogenous antibodies not specific for arsonate
A new cross-reactive idiotope family (CRIAD8) is described that contains subpopulations of antibodies binding to different… Expand
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1982
1982
Lack of inter-animal cross-reaction of anti-acetylcholine receptor antibodies at the receptor-binding site as demonstrated by heterologous anti-idiotype antisera: implications for immunotherapy of…
Anti-idiotype antisera were raised in rabbits by immunization with purified sheep anti-Torpedo receptor antibodies. The antisera… Expand
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