monoclonal antibody 4B5 anti-idiotype vaccine
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Significance Idiotype is a true tumor-specific surface marker on lymphoma cells, and cross-linking idiotype can directly trigger… Expand We have used a well‐defined idiotypic system, the cross‐reactive idiotype of A strain (CRIA) (Ab1) idiotype generated in A/J mice… Expand Using idiotypic analysis, we examined the variable (V) region diversity of human antibodies specific for the capsular… Expand A new common idiotype, designated PR4, is described. This idiotype was originally identified on a human hybridoma-derived… Expand BALB/c and BALB/c nu/nu mice were shown to express to a variable extent in their response against dextran B1355S (Dex), an… Expand We have shown that, by suitable idiotypic manipulation, BALB/c mice can express the major cross-reactive idiotype (CRI) of A/J… Expand A new cross-reactive idiotope family (CRIAD8) is described that contains subpopulations of antibodies binding to different… Expand Anti-idiotype antisera were raised in rabbits by immunization with purified sheep anti-Torpedo receptor antibodies. The antisera… Expand The development of HOPC-8 idiotype-positive and HOPC-8 idiotype-negative B cell subpopulations involved in the immune response to… Expand An anti‐idiotypic antiserum specific for the antibodies directed against the terpolymer poly(Glu60, Ala30, Tyr10), referred to as… Expand