FAQ

mitogen-activated protein kinase binding

Known as: MAP kinase binding, MAPK binding 
Interacting selectively and non-covalently with a mitogen-activated protein kinase. [GOC:ai]

Topic mentions per year

Topic mentions per year

1998-2016
02419982016

Papers overview

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2012
2012
Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove.
Mitogen-activated protein kinases (MAPKs) have a docking groove that interacts with linear "docking" motifs in binding partners… (More)
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2012
2012
Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity.
RUNX2, a key transcription factor for osteoblast differentiation, is regulated by ERK1/2 and p38 MAP kinase-mediated… (More)
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2011
2011
A distinct interaction mode revealed by the crystal structure of the kinase p38α with the MAPK binding domain of the phosphatase MKP5.
The mitogen-activated protein kinase (MAPK) cascades play a pivotal role in a myriad of cellular functions… (More)
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2003
2003
Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
Mitogen-activated protein kinase (MAPK) cascades control gene expression patterns in response to extracellular stimuli. MAPK/ERK… (More)
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Highly Cited
2001
Highly Cited
2001
Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1.
Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1/CL100) is an inducible nuclear dual specificity protein phosphatase… (More)
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Highly Cited
2000
Highly Cited
2000
SIMKK, a mitogen-activated protein kinase (MAPK) kinase, is a specific activator of the salt stress-induced MAPK, SIMK.
In eukaryotes, mitogen-activated protein kinases (MAPKs) play key roles in the transmission of external signals, such as mitogens… (More)
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Highly Cited
2000
Highly Cited
2000
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR…
The cAMP-specific phosphodiesterase family 4, subfamily D, isoform 3 (PDE4D3) is shown to have FQF and KIM docking sites for… (More)
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Highly Cited
1999
Highly Cited
1999
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase.
MAP kinases phosphorylate specific groups of substrate proteins. Here we show that the amino acid sequence FXFP is an… (More)
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Highly Cited
1999
Highly Cited
1999
Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression.
Genetic and biochemical studies have identified kinase suppressor of Ras (KSR) to be a conserved component of Ras-dependent… (More)
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1998
1998
Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and…
We have isolated the human genes encoding the Pyst1 (MKP-3) and Pyst2 (MKP-X) MAP kinase phosphatases. Both genes consist of… (More)
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