mitochondrial permeability transition pore

Known as: mPTP protein, cyclosporin A-SPTP, mitochondrial megachannel (MMC) 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Axonal degeneration is an active process that has been associated with neurodegenerative conditions triggered by mechanical… (More)
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Review
2009
Review
2009
Under conditions of mitochondrial calcium overload, especially when accompanied by oxidative stress, elevated phosphate… (More)
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Review
2009
Review
2009
Like Dr. Jeckyll and Mr. Hyde, mitochondria possess two distinct persona. Under normal physiological conditions they synthesise… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE The opening of the mitochondrial permeability transition pore (mPTP) at the time of myocardial reperfusion is a… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Brief periods of ischemia performed just at the time of reperfusion can reduce infarct size, a phenomenon called… (More)
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Highly Cited
2004
Highly Cited
2004
A sudden increase in permeability of the inner mitochondrial membrane, the so-called mitochondrial permeability transition, is a… (More)
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Review
2004
Review
2004
Reperfusion of the heart after a period of ischaemia leads to the opening of a nonspecific pore in the inner mitochondrial… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE The opening of the mitochondrial permeability transition pore (mPTP) in the first few minutes of post-ischaemic… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE We propose that ischemic preconditioning (IPC) and mitochondrial K(ATP) channel activation protect the myocardium by… (More)
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Review
2002
Review
2002
Mitochondria play a critical role in initiating both apoptotic and necrotic cell death. A major player in this process is the… (More)
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