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mitochondrial outer membrane fusion

The membrane organization process that joins two mitochondrial outer membranes to form a single membrane. [GOC:vw, PMID:21385840]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells.
Leukemia is a type of hematopoietic stem cell malignant cloned disease with high mortality. Cisplatin-based chemotherapy is one… 
Highly Cited
2014
Highly Cited
2014
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Highly Cited
2014
Highly Cited
2014
MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons*♦
Background: Mitochondrial function is dependent on mitochondrial fission and fusion dynamics. Results: Calpain-mediated… 
2012
2012
Regulation of Mitochondrial Outer Membrane Fusion by the Mitofusin Fzo1
Mitochondria are essential organelles in all eukaryotic cells forming a tubular and dynamic network undergoing constant fusion… 
Highly Cited
2012
Highly Cited
2012
Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.
Highly Cited
2012
Highly Cited
2012
Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca2+ Crosstalk
Rationale: Mitochondrial Ca2+ uptake is essential for the bioenergetic feedback response through stimulation of Krebs cycle… 
Highly Cited
2011
Highly Cited
2011
Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion
The ability of cells to respire requires that mitochondria undergo fusion and fission of their outer and inner membranes. The… 
Highly Cited
2011
Highly Cited
2011
Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
Dynamin-related GTPase proteins (DRPs) are main players in membrane remodelling. Conserved DRPs called mitofusins (Mfn1/Mfn2/Fzo1… 
2009
2009
Targeting bioenergetics to enhance cancer chemotherapy: Mitochondria SLP into apoptosis
Commentary to: Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances… 
Review
2006
Review
2006
Get the balance right: mitofusins roles in health and disease.
  • A. Santel
  • Biochimica et biophysica acta
  • 2006
  • Corpus ID: 30373071
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