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mitochondrial outer membrane fusion

The membrane organization process that joins two mitochondrial outer membranes to form a single membrane. [GOC:vw, PMID:21385840]
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Mitochondrial fusion is essential for maintenance of mitochondrial function. The mitofusin GTPases control mitochondrial outer… Expand
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Highly Cited
2014
Highly Cited
2014
MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons*♦
Background: Mitochondrial function is dependent on mitochondrial fission and fusion dynamics. Results: Calpain-mediated… Expand
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2013
2013
Regulation of Mitochondrial Outer Membrane Fusion by the Mitofusin Fzo 1 Zusammenfassung
  • 2013
    • Corpus ID: 55027505
Mitochondrien sind essentielle Organellen in allen eukaryotischen Zellen. Sie bilden ein tubuläres und dynamisches Netzwerk, das… Expand
2012
2012
Regulation of Mitochondrial Outer Membrane Fusion by the Mitofusin Fzo1
 
Highly Cited
2012
Highly Cited
2012
Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca2+ Crosstalk
Rationale: Mitochondrial Ca2+ uptake is essential for the bioenergetic feedback response through stimulation of Krebs cycle… Expand
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Highly Cited
2012
Highly Cited
2012
Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.
Mitochondria play central roles in integrating pro- and antiapoptotic stimuli, and JNK is well known to have roles in activating… Expand
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Highly Cited
2011
Highly Cited
2011
Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion
The ability of cells to respire requires that mitochondria undergo fusion and fission of their outer and inner membranes. The… Expand
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Highly Cited
2011
Highly Cited
2011
Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
Dynamin-related GTPase proteins (DRPs) are main players in membrane remodelling. Conserved DRPs called mitofusins (Mfn1/Mfn2/Fzo1… Expand
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2009
2009
Targeting bioenergetics to enhance cancer chemotherapy: Mitochondria SLP into apoptosis
Commentary to: Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances… Expand
Review
2006
Review
2006
Get the balance right: mitofusins roles in health and disease.
  • A. Santel
  • Biochimica et biophysica acta
  • 2006
    • Corpus ID: 30373071
Mitochondria are highly dynamic organelles exhibiting an elaborate morphology and fine structure. Fusion and fission processes… Expand
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