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mitochondrial membrane permeabilization

 
National Institutes of Health

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Topic mentions per year

2000-2016
02420002016

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positive regulation of mitochondrial membrane permeability

Related mentions per year

Related mentions per year

1965-2018
1960198020002020
mitochondrial membrane permeabilization
positive regulation of mitochondrial membrane permeability

Papers overview

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2015
2015
The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization
LTX-315 has been developed as an amphipathic cationic peptide that kills cancer cells. Here, we investigated the putative… (More)
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Review
2009
Review
2009
Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection.
Recent data have provided important clues about the molecular mechanisms underlying certain neurodegenerative diseases. Most cell… (More)
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2008
2008
Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis.
In several paradigms of cell death, mitochondrial membrane permeabilization (MMP) delimits the frontier between life and death… (More)
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Highly Cited
2008
Highly Cited
2008
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death
Following the screening of a battery of distinct small-interfering RNAs that target various components of the apoptotic machinery… (More)
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Review
2007
Review
2007
Mitochondrial membrane permeabilization in cell death.
Irrespective of the morphological features of end-stage cell death (that may be apoptotic, necrotic, autophagic, or mitotic… (More)
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Highly Cited
2003
Highly Cited
2003
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
Hydroxychloroquine (HCQ) is a lysosomotropic amine with cytotoxic properties. Here, we show that HCQ induces signs of lysosomal… (More)
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Highly Cited
2002
Highly Cited
2002
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
Accumulating evidence suggests that mitochondrial membrane permeabilization (MMP) is a rate-limiting step of programmed… (More)
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2002
2002
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway
Previous biochemical studies suggested that HIV-1-encoded Vpr may kill cells through an effect on the adenine nucleotide… (More)
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Highly Cited
2001
Highly Cited
2001
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437
An increasing number of experimental chemotherapeutic agents induce apoptosis by directly triggering mitochondrial membrane… (More)
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Highly Cited
2000
Highly Cited
2000
Bid acts on the permeability transition pore complex to induce apoptosis
Similar to most if not all pro-apoptotic members of the Bcl-2 family, Bid (and its truncated product t-Bid) triggers cell death… (More)
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