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mitochondrial membrane permeabilization

 
National Institutes of Health

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Broader (1)

positive regulation of mitochondrial membrane permeability

Papers overview

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Highly Cited
2010
Highly Cited
2010
Glutathionylation of adenine nucleotide translocase induced by carbon monoxide prevents mitochondrial membrane permeabilization and apoptosis.
The present work demonstrates the ability of CO to prevent apoptosis in a primary culture of astrocytes. For the first time, the… Expand
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Highly Cited
2009
Highly Cited
2009
GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis.
Mitochondria-associated ER membranes, or MAMs, define the sites of endoplasmic reticulum/mitochondria juxtaposition that control… Expand
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Review
2007
Review
2007
Mitochondrial membrane permeabilization in cell death.
Irrespective of the morphological features of end-stage cell death (that may be apoptotic, necrotic, autophagic, or mitotic… Expand
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Review
2007
Review
2007
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis
Mitochondrial membrane permeabilization (MMP) is considered as the “point-of-no-return” in numerous models of programmed cell… Expand
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Highly Cited
2005
Highly Cited
2005
Mitochondrial permeability transition in apoptosis and necrosis
Apoptosis has classically been viewed as a process not involving mitochondria, whereas the implication of mitochondrial… Expand
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Highly Cited
2003
Highly Cited
2003
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
Hydroxychloroquine (HCQ) is a lysosomotropic amine with cytotoxic properties. Here, we show that HCQ induces signs of lysosomal… Expand
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Highly Cited
2003
Highly Cited
2003
Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion
A number of diseases are due to lysosomal destabilization, which results in damaging cell loss. To investigate the mechanisms of… Expand
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Review
2002
Review
2002
Chemotherapy: targeting the mitochondrial cell death pathway
One of the mechanisms by which chemotherapeutics destroy cancer cells is by inducing apoptosis. Apoptosis can be activated… Expand
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Review
2001
Review
2001
Organelle-specific initiation of cell death pathways
Nuclear DNA damage and ligation of plasma-membrane death receptors have long been recognized as initial triggers of apoptosis… Expand
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Highly Cited
2001
Highly Cited
2001
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437
An increasing number of experimental chemotherapeutic agents induce apoptosis by directly triggering mitochondrial membrane… Expand
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